Results 81 to 90 of about 330,584 (291)

Phase diagram of neutron-rich nuclear matter and its impact on astrophysics

, 2012
Dense matter as it can be found in core-collapse supernovae and neutron stars is expected to exhibit different phase transitions which impact the matter composition and equation of state, with important consequences on the dynamics of core-collapse ...
Ad R Raduta, Bednarek I, Ducoin C, F Gulminelli, Gulminelli F, J Margueron, M Oertel, Marek A, Massot E, Nakazato K, Ozel F, P Papakonstantinou, Phillips A C, Shetty D V, Souza S R, Vidana I   +15 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Transparent subdiffraction optics: nanoscale light confinement without metal

, 2014
The integration of nanoscale electronics with conventional optical devices is restricted by the diffraction limit of light. Metals can confine light at the subwavelength scales needed, but they are lossy, while dielectric materials do not confine ...
Jacob, Zubin, Jahani, Saman
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Selecting the best distribution for modeling trends in low, medium, and extreme daily precipitation under climate change [PDF]

Advances in Statistical Climatology, Meteorology and Oceanography
Changes in mean precipitation and the frequency and intensity of extreme precipitation represent one of the most consequential aspects of anthropogenic climate change. This study evaluates a set of statistical distributions for modeling trends across the
A. Haruna, J. Blanchet, G. Evin, E. Paquet   +3 more
doaj   +1 more source

Phonons and specific heat of linear dense phases of atoms physisorbed in the grooves of carbon nanotube bundles

, 2002
The vibrational properties (phonons) of a one-dimensional periodic phase of atoms physisorbed in the external groove of the carbon nanotube bundle are studied. Analytical expressions for the phonon dispersion relations are derived.
A. Thess, A. Šiber, A. Šiber, A. Šiber, A.J. Zambano, A.P. Graham, A.P. Graham, Antonio Šiber, Ch. Wöll, G. Stan, G. Stan, J. Braun, J. Hone, J.C. Lasjaunias, J.R. Klein, L.W. Bruch, L.W. Bruch, M.K. Kostov, M.M. Calbi, M.M. Calbi, M.W. Cole, P.S. Bagus, R.E. Allen, S. Talapatra, S.E. Weber, S.M. Gatica, W. Teizer   +26 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Multi-Frequency VLBA Polarimetry and the Twin-Jet Quasar 0850+581

Galaxies, 2017
We present the first multi-frequency VLBA study of the quasar 0850+581 which appears to have a two-sided relativistic jet. Apparent velocity in the approaching jet changes from 3.4c to 7c with the separation from the core. The jet-to-counter-jet ratio of
Evgeniya Kravchenko, Yuri Y. Kovalev
doaj   +1 more source

Quenching of high-pT hadrons: Energy Loss vs Color Transparency

, 2012
High-pT hadrons produced in hard collisions and detected inclusively bear peculiar features: (i) they originate from jets whose initial virtuality and energy are of the same order; (ii) such jets are rare and have a very biased energy sharing among the ...
B. G. Zakharov, B. G. Zakharov, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, B. Z. Kopeliovich, I. K. Potashnikova, Iván Schmidt, J. Nemchik, V. A. Abramovsky, V. A. Abramovsky   +12 more
core   +1 more source