Results 61 to 70 of about 55,761 (291)

Dense medium separation : A dynamic model and medium loss analysis [PDF]

Dissertation (MEng(Electronic Engineering))--University of Pretoria, 2017.In this study, a model of a dense medium separation circuit of an iron ore plant in South Africa is developed, focusing on the flow of medium in the circuit. The model is validated

core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Design of Medium Density Control System in Dense-medium Separation Based on Fuzzy Control

Gong-kuang zidonghua, 2012
In view of problem of bad control effect because of manual control for medium density control in dense-medium separation in one coal preparation plant, medium density control system based on fuzzy control was designed.
SUN Yun-xiao, MA Xiao-ping, WANG Wei-bo
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Some causes of medium loss in dense medium plants.

, 1995
Medium consumption is a significant component of the cost of operating a dense medium plant. This study aimed to identify and quantify many of the factors contributing to overall consumption, through extensive surveys of four widely differing dense ...
Kojovic, T., Masinja, J. H., Napier-Munn, T. J., Shi, F. N., Scott, I. A., Baguley, P. J.   +5 more
core   +1 more source

Coexistence of jaguars (Panthera onca) and pumas (Puma concolor) in a tropical forest in south-eastern Mexico

Animal Biodiversity and Conservation, 2020
The biological ranges of the jaguar (Panthera onca) and puma (Puma concolor) overlap in the Yucatan Peninsula, corresponding to the most important population of jaguars in Mexico.
D. M. Ávila–Nájera, C. Chávez, S. Pérez–Elizalde, J. Palacios–Pérez, B. Tigar   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A dual-loop control system for dense medium coal washing processes with sampled and delayed measurements [PDF]

, 2017
A dual closed-loop control system is developed for a dense medium coal washing process. The controller is designed to improve the separation efficiency and energy efficiency of the dense medium cyclone coal beneficiation process simultaneously making use
Zhu, Bing, Xia, Xiaohua, Zhang, Lijun
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Selecting the best distribution for modeling trends in low, medium, and extreme daily precipitation under climate change [PDF]

Advances in Statistical Climatology, Meteorology and Oceanography
Changes in mean precipitation and the frequency and intensity of extreme precipitation represent one of the most consequential aspects of anthropogenic climate change. This study evaluates a set of statistical distributions for modeling trends across the
A. Haruna, J. Blanchet, G. Evin, E. Paquet   +3 more
doaj   +1 more source