Results 111 to 120 of about 181,532 (295)

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Numerical study on deuteron beams properties generated from dense plasma focus devices in terms of D2 gas pressure using Lee model code

مجلة جامعة دمشق للعلوم الأساسية
Using Lee model code (RADPFV5.16FIB), numerical experiments on deuteron beams properties emitted from five Dense Plasma Focus (DPF) devices (PF1000, TAMU, UNU-ICTP, NX2T, PF400) were performed and compared with each other at low- and high-pressures in a
abdaljalil Muheialdeen altarabulsi, Yousef Mohmaud Adou-ali, Sami Mustafa Alsheikh Salo   +2 more
doaj  

Pinching relativistic electrons in the quantum degenerate plasmas to enhance the fast heating

High Power Laser Science and Engineering
The transport process of a relativistic electron beam (REB) in high-density and degenerate plasmas holds significant importance for fast ignition. In this study, we have formulated a comprehensive theoretical model to address this issue, incorporating ...
Y.-H. Li, D. Wu, J. Zhang
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Inner screening corrections to the Debye interaction in hot/dense plasmas in the vicinity of the bound – free transitions

Physical Sciences and Technology, 2020
Considering hot/dense plasmas strongly ionized and still retaining hydrogenic bound states (1 ≤ z ≤ 6), we focus attention on the delocalization features of ion-electron orbitals, such as wide spreading and attending of pertaining wave functions close ...
C. Deutsch, G. Naouri, N. A. Tahir
doaj  

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Ion emission from warm dense matter produced by irradiation with a soft x-ray free-electron laser

Matter and Radiation at Extremes
We report on an experiment performed at the FLASH2 free-electron laser (FEL) aimed at producing warm dense matter via soft x-ray isochoric heating. In the experiment, we focus on study of the ions emitted during the soft x-ray ablation process using time-
Josef Krása, Tomáš Burian, Věra Hájková, Jaromír Chalupský, Šimon Jelínek, Kateřina Frantálová, Michal Krupka, Zuzana Kuglerová, Sushil Kumar Singh, Vojtěch Vozda, Luděk Vyšín, Michal Šmíd, Pablo Perez-Martin, Marion Kühlman, Juan Pintor, Jakub Cikhardt, Matthias Dreimann, Dennis Eckermann, Felix Rosenthal, Sam M. Vinko, Alessandro Forte, Thomas Gawne, Thomas Campbell, Shenyuan Ren, YuanFeng Shi, Trevor Hutchinson, Oliver Humphries, Thomas Preston, Mikako Makita, Motoaki Nakatsutsumi, Xiayun Pan, Alexander Köhler, Marion Harmand, Sven Toleikis, Katerina Falk, Libor Juha   +35 more
doaj   +1 more source

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah, Sangmee S Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source