Results 141 to 150 of about 170,031 (283)

Osteological, Biological, and Genetic Consequences of Colonization of Fresh Waters by Marine Cottoid Fishes (Cottidae)

Integrative Zoology, EarlyView.
Lacustrine forms of Triglopsis from North American and European lakes are at different stages of evolution, making them a suitable model for testing hypotheses about evolutionary patterns and rates. An integrative analysis of morphological, genetic, and biological adaptations occurring in lacustrine forms of the genus Triglopsis was carried out.
Valentina G. Sideleva, Zakhar V. Zhidkov, Nataliia V. Annenkova, Alexander G. Ryumin, Danila A. Melentev   +4 more
wiley   +1 more source

Changes in corneal aberrations and densitometry after diamond burr superficial keratectomy in post-traumatic recurrent corneal erosion: A retrospective observational study. [PDF]

Medicine (Baltimore)
Tsai HH, Ho WT.
europepmc   +1 more source

Transgender and Gender Diverse Patient Experiences, Care and Health Outcomes in Medical Imaging: A Scoping Review

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Changes in legislation and social attitudes towards transgender and gender diverse (TGD) people have prompted clinical and ethical questions about the experiences, care, and health outcomes of TGD patients in medical imaging. Aim The aim of this scoping review is to identify the main themes surrounding TGD patient care in medical ...
Kirralee Jane Davies, Ricky Lam
wiley   +1 more source

Klebsiella pneumoniae inhibits vasodilation through capsule and T6SS-dependent pathways. [PDF]

Nat Microbiol
Rehman S, Sa-Pessoa J, Buckley C, Lee RL, Wojtania K, Lee A, Lancaster R, Augustine J, Barabas P, Ross C, Zhang X, McCarron JG, Curtis TM, Bengoechea JA.   +13 more
europepmc   +1 more source

CD47 promotes myeloma cell growth through JAK–STAT3/MYC signalling and is targetable by ruxolitinib

British Journal of Haematology, EarlyView.
Summary Cluster of differentiation 47 (CD47), a ‘don't eat me’ immune checkpoint receptor, is frequently overexpressed on multiple myeloma (MM) cells and contributes to immune evasion. While its immune regulatory function is well established, the intrinsic oncogenic role of CD47 remains poorly understood.
Omar Faruq, Deepak Iyer, Patrick Wang, Mariusz Shrestha, Cuihong Wei, Aaron D. Schimmer, Hong Chang   +6 more
wiley   +1 more source

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

Brain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau, Nicholas R. G. Silver, Surabhi Mehra, Raphaella W. L. So, Le yao Li, Alison Mao, Erica Stuart, Cian Schmitt‐Ulms, Bradley T. Hyman, Martin Ingelsson, Joel C. Watts   +10 more
wiley   +1 more source

Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets. [PDF]

FASEB J
Parolini I, Bellina A, Carpi G, Diatlova EA, Lippe G, Fontanini E, Barillari G, Isola M, Beltrami AP, Tell G.   +9 more
europepmc   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Sex-specific trends in hip fracture incidence and disparities in DXA utilization in Brazil: a nationwide ecological analysis. [PDF]

Arch Osteoporos
Januário I, Albergaria BH, Teixeira BC, Lazaretti-Castro M.   +3 more
europepmc   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source