Results 201 to 210 of about 170,031 (283)

The methyltransferase Rrp8 is a positive regulator of autophagy flux in <i>Saccharomyces cerevisiae</i>. [PDF]

MicroPubl Biol
Badenahalli Narasimhaiah S, Delorme-Axford E.   +1 more
europepmc   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Corneal Structural Alterations Under Chronic Hyperglycemia: Biomechanical and Densitometric Insights in Type 2 Diabetes with and Without Retinopathy. [PDF]

Beyoglu Eye J
Aydin FO, Akbas YB, Ceylan A, Ermis S, Afsin BA, Yildiz BK.   +5 more
europepmc   +1 more source

FGF21/sirtuin 1 axis mediates the cardioprotective effects of high‐intensity interval training against doxorubicin‐induced cardiotoxicity by reducing inflammatory and oxidative stress

Experimental Physiology, EarlyView.
Abstract Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent, but its clinical use is limited by cumulative cardiotoxicity. Exercise, particularly high‐intensity interval training (HIIT), has emerged as an effective non‐pharmacological strategy to counteract chemotherapy‐induced cardiac injury.
Mahdiyeh Farahani, Abbas Ali Gaeini, Alireza Ghardashi Afousi, Mahboobeh Borjian Fard   +3 more
wiley   +1 more source

SPP1 integrates trophoblast-endothelial crosstalk via the αVβ3-PI3K/Akt-MMP-9 axis to govern vascular remodeling in preeclampsia. [PDF]

Mol Biol Rep
Ma X, Kong H, Wang F, Su Y, Chang Y, Xin H.   +5 more
europepmc   +1 more source

Early‐stage 2K1C renovascular hypertension does not increase global MHC‐II or F4/80 abundance in the non‐clipped kidney but reveals focal F4/80+ induction

Experimental Physiology, EarlyView.
Abstract The two‐kidney, one‐clip (2K1C) model produces renovascular hypertension. The effects on the clipped kidney (CK) are well described, while the non‐clipped kidney (NCK) is used as a model to evaluate the effects of high blood pressure. Although most of these effects have been described at later stages of 2K1C hypertension, it remains unclear ...
Pilar Cárdenas, Allison C. León, Juan Castillo‐Geraldo, Catalina Cid‐Salinas, Javiera Saez, Stefanny Figueroa, Javier Reyes, Emma Rosenkoetter, Suarybell Guzmán Román, Carmen De Miguel, Cristián A. Amador, Alexis A Gonzalez   +11 more
wiley   +1 more source

Corneal densitometry and its association with cumulative dissipated energy after phacoemulsification. [PDF]

BMC Ophthalmol
Furuncuoglu U, Uslubas I, Toprak M.
europepmc   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats. [PDF]

Acta Biochim Pol
Papageorgiou A, Sofiou FI, Philippou A, Gkrampovari M, Agiannitopoulos K, Traikov L.   +5 more
europepmc   +1 more source