Results 201 to 210 of about 248,416 (349)

Tree species diversity drives above‐ground carbon sequestration through light‐related trait shifts

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Functional traits can vary in response to tree species mixing, which in turn might influence biomass production and, consequently, carbon (C) sequestration in diverse forests.
Joel Jensen   +41 more
wiley   +1 more source

Transgender and Gender Diverse Patient Experiences, Care and Health Outcomes in Medical Imaging: A Scoping Review

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Changes in legislation and social attitudes towards transgender and gender diverse (TGD) people have prompted clinical and ethical questions about the experiences, care, and health outcomes of TGD patients in medical imaging. Aim The aim of this scoping review is to identify the main themes surrounding TGD patient care in medical ...
Kirralee Jane Davies, Ricky Lam
wiley   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

open access: yesAndrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda   +7 more
wiley   +1 more source

α-ketoglutarate/succinate ratio imbalance impairs thymine DNA glycosylase function and base excision repair process increasing susceptibility to pancreatic cancer. [PDF]

open access: yesCell Death Dis
Malatesta S   +20 more
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

PFKM governs metabolic shifts throughout skeletal muscle differentiation. [PDF]

open access: yesNat Metab
Campos M   +22 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

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