Results 51 to 60 of about 1,733,991 (287)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Improved Density and Distribution Function Estimation
, 2018 Given additional distributional information in the form of moment restrictions, kernel density and distribution function estimators with implied generalised empirical likelihood probabilities as weights achieve a reduction in variance due to the ...
Oryshchenko, Vitaliy, Smith, Richard J.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sheep Counting Method Based on Multiscale Module Deep Neural Network
IEEE Access, 2022 Due to the uneven distribution and large scale change of sheep in the pasture, it is not conducive to the counting and statistics of sheep in animal husbandry.
Jianming Xu +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Asymptotic unbiased density estimators [PDF]
ESAIM: Probability and Statistics, 2009 Summary: This paper introduces a computationally tractable density estimator that has the same asymptotic variance as the classical Nadaraya-Watson density estimator but whose asymptotic bias is zero. We achieve this result using a two stage estimator that applies a multiplicative bias correction to an oversmooth pilot estimator.
Hengartner, Nicolas W. +1 more
openaire +4 more sources
Shifting foundations and metrics for golden‐cheeked warbler recovery
Wildlife Society Bulletin, 2012 Using the golden‐cheeked warbler (Setophaga chrysoparia) as a case study, this paper discusses what lessons can be learned from the process of the emergency listing and subsequent development of the recovery plan.
Jeff S. Hatfield +2 more
doaj +1 more source
Adaptive Density Estimation for Generative Models [PDF]
, 2019 Unsupervised learning of generative models has seen tremendous progress over recent years, in particular due to generative adversarial networks (GANs), variational autoencoders, and flow-based models.
Alahari, Karteek +4 more
core +2 more sources
Information geometry of density matrices and state estimation
, 2011 Given a pure state vector |x> and a density matrix rho, the function p(x|rho)= defines a probability density on the space of pure states parameterised by density matrices.
Amari S +6 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source