Results 111 to 120 of about 5,390,161 (308)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Individual differences, density dependence and offspring birth traits in a population of red deer [PDF]

open access: yes, 2008
Variation between individuals is an essential component of natural selection and evolutionary change, but it is only recently that the consequences of persistent differences between individuals on population dynamics have been considered.
Clutton-Brock, TH   +8 more
core   +1 more source

Evolution of Phonon Spectral Energy Density in Superlattice Structures

open access: yesCrystals
Superlattices are a distinctive class of artificial nanostructures formed by the periodic stacking of two or more materials. The high density of interfaces in these structures often gives rise to exotic physical properties.
Milad Nasiri, Yan Wang
doaj   +1 more source

Energy Flows in Low-Entropy Complex Systems

open access: yesEntropy, 2015
Nature’s many complex systems—physical, biological, and cultural—are islands of low-entropy order within increasingly disordered seas of surrounding, high-entropy chaos.
Eric J. Chaisson
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

POPULATION DEMOGRAPHY AND THE EVOLUTION OF HELPING BEHAVIORS

open access: yes, 2006
International audienceLimited dispersal may favor the evolution of helping behaviors between relatives as it increases their relatedness, and it may inhibit such evolution as it increases local competition between these relatives.
Perrin, N.   +4 more
core   +1 more source

A spatially explicit capture-recapture estimator for single-catch traps [PDF]

open access: yes, 2015
This work was part-funded by EPSRC grant EP/I000917/1.1. Single-catch traps are frequently used in live-trapping studies of small mammals. Thus far a likelihood for single-catch traps has proven elusive and usually the likelihood for multi-catch traps is
Distiller, Greg   +3 more
core   +1 more source

Evolution of density structures in the inner magnetosphere using coordinated Van Allen probe observations

open access: yesFrontiers in Astronomy and Space Sciences
The plasmasphere contains rich small-scale structure that plays a key role in regulating wave propagation and mass transport in the inner magnetosphere, yet the evolution of plasmaspheric density ducts remains poorly understood. We use joint observations
Tyler Bishop, Lauren Blum
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Quasar number density evolution

open access: yesThe Astrophysical Journal, 1981
A simple model of quasar number density evolution is presented based on the occurrence of quasar-like radio galaxies (i.e., strong optical emission lines and type 2 radio morphology) exclusively in regions of low galaxy and intergalactic medium (IGM) density.
J. T. Stocke, S. C. Perrenod
openaire   +1 more source

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