Results 91 to 100 of about 5,390,161 (308)

Complex Adaptations and the Evolution of Evolvability

open access: yes, 2005
Complex Adaptations and the Evolution of Evolvability +representation problem: "evolvability critically depends on the way genetic variation maps onto phenotypic variation" +Evidence that phenotypic variation is under genetic control: canalization ...
Altenberg, Lee, Wagner, Gunter P.
core  

Italian Multicenter Study on Low-Density Lipoprotein Apheresis Working Group 2009 Survey

open access: yes, 2013
We present results of the second survey of the Italian Multicenter Study on Low-Density Lipoprotein Apheresis (IMSLDLa-WG/2). The study involved 18 centers in 2009, treating 66 males and 35 females, mean age 47 +/- 18 years.
MOROZZI, CLAUDIA   +3 more
core   +1 more source

The stability of the variable-density Kelvin-Helmholtz billow [PDF]

open access: yes, 2008
We perform a three-dimensional stability analysis of the Kelvin-Helmholtz billow, developing in a shear-layer between two fluids with different density.
Fontane, Jérôme, Joly, Laurent
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Effects of anti-resorptive agents on trabecular bone score (TBS) in older women.

open access: yes, 2013
We evaluated the longitudinal effects of anti-resorptive agents (534 treated women vs. 1,150 untreated) on lumbar spine bone mineral density (BMD) and trabecular bone score (TBS). TBS was responsive to treatment in women over age 50.
Aubry-Rozier, B.   +4 more
core   +1 more source

Construction of Rate-Compatible LDPC Codes Utilizing Information Shortening and Parity Puncturing

open access: yesEURASIP Journal on Wireless Communications and Networking, 2005
This paper proposes a method for constructing rate-compatible low-density parity-check (LDPC) codes. The construction considers the problem of optimizing a family of rate-compatible degree distributions as well as the placement of bipartite graph edges.
Jones Christopher R, Tian Tao
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Does Clade Density Constrain Geographical Range Evolution?

open access: yesEcology and Evolution
The role of biotic interactions, such as interspecific competition, in driving geographical range evolution is still poorly understood. For instance, lineages distributed across regions with a large number of potential competitors might experience some ...
Marcio R. Pie   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The density evolution of IRAS galaxies

open access: yesThe Astrophysical Journal, 1992
A maximum likelihood test for density evolution is applied to a full-sky redshift survey of 5297 galaxies selected from the IRAS data base and flux-limited at 1.2 Jy. No evidence for evolution is found. Attention is given to important systematic errors which decrease the certainty with which evolution can be measured, namely, limited knowledge of the ...
Karl B. Fisher   +4 more
openaire   +1 more source

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