Results 31 to 40 of about 2,179,940 (251)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Vector potential versus colour charge density in low-x evolution [PDF]

, 1999
We reconsider the evolution equations for multigluon correlators derived in hep-ph/9709432. We show how to derive these equations directly in terms of vector potentials (or colour field strength) avoiding the introduction of the concept of colour charge ...
A. H. Mueller, A. H. Mueller, A. L. Ayala, A. Mueller, Alex Kovner, E. A. Kuraev, E. Gotsman, E. Gotsman, J. Guilherme Milhano, J. Jalilian-Marian, J. Jalilian-Marian, J. Jalilian-Marian, J. Jalilian-Marian, J. Jalilian-Marian, J. Jalilian-Marian, J. Jalilian-Marian, L. McLerran, L. McLerran, L. V. Gribov, R. Gavai, V. Khoze, Ya. Ya. Balitsky, Yu. Kovchegov   +22 more
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Evolution of an N-level system via automated vectorization of the Liouville equations and application to optically controlled polarization rotation

, 2013
The Liouville equation governing the evolution of the density matrix for an atomic/molecular system is expressed in terms of a commutator between the density matrix and the Hamiltonian, along with terms that account for decay and redistribution.
Krishnamurthy, Subramanian, Pati, G. S., Shahriar, M. S., Tseng, S., Tu, Y., Wang, Ye   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Stellar Mass and Velocity Functions of Galaxies: Backward evolution and the fate of Milky Way siblings [PDF]

, 2010
We attempt in this paper to check the consistency of the observed Stellar Mass Function (SMF), SFR functions and the cosmic star formation rate density with simple backward evolutionary models. Starting from observed SMF for star-forming galaxies, we use
Arnouts, Bell, Bell, Bell, Boissier, Boissier, Boissier, Boissier, Boissier, Borch, Brinchmann, Brown, Buat, Bundy, Bundy, Cowie, Daddi, Davé, de Ravel, Di Matteo, Eke, Elbaz, Faber, Gavazzi, Gonzalez, Hopkins, Hopkins, Ilbert, Jogee, Kennicutt, Khochfar, Kilborn, Koda, Kroupa, Kroupa, Le Floc’h, Lewis, Lotz, López-Sanjuan, Magnelli, Martig, Melbourne, Neichel, Noeske, O. Ilbert, Oesch, Pérez-González, Robaina, Rodighiero, S. Boissier, Sanders, Santini, Shapiro, Springel, Tanaka, Tanaka, Tran, V. Buat, Vergani, Wilkins   +59 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source