Results 41 to 50 of about 467,902 (217)
Density functional theory analysis of hydrogen evolution of cluster Mo3S4
In order to explore the hydrogen evolution mechanism at the micro level of cluster Mo3S4, the full-parameter optimization and frequency calculation of cluster Mo3S4 in single and triple states were carried out based on the B3LYP level of density ...
Yiwen ZHU +5 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Community Detection Based on Differential Evolution Using Modularity Density
Currently, many community detection methods are proposed in the network science field. However, most contemporary methods only employ modularity to detect communities, which may not be adequate to represent the real community structure of networks for ...
Caihong Liu, Qiang Liu
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
To evaluate the effect of nonparallel end face of rocklike specimens in SHPB tests, the characteristics of energy dissipation are analyzed based on numerical simulations for end-face nonparallelism from 0% to 0.40% and Young’s modulus from 14 GPa to 42 ...
Pu Yuan, Ning-Ning Wei, Qin-Yong Ma
doaj +1 more source
Evolution of Charge and Pair Density Modulations in Overdoped Bi_{2}Sr_{2}CuO_{6+δ}
One of the central issues concerning the mechanism of high-temperature superconductivity in cuprates is the nature of the ubiquitous charge order and its implications to superconductivity.
Xintong Li +9 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

