Results 61 to 70 of about 467,902 (217)

Does Clade Density Constrain Geographical Range Evolution?

open access: yesEcology and Evolution
The role of biotic interactions, such as interspecific competition, in driving geographical range evolution is still poorly understood. For instance, lineages distributed across regions with a large number of potential competitors might experience some ...
Marcio R. Pie   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A dislocation-based model for the substructure evolution and flow stress of aluminum alloys during high-temperature compression

open access: yesJournal of Materials Research and Technology
The microstructure evolution of aluminum alloys during plastic deformation is a complex metallurgical process controlled by interacting physical mechanisms, such as recovery, continuous dynamic recrystallization (CDRX), and substructure evolution.
Qi Yang, Tomasz Wojcik, Ernst Kozeschnik
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Energy Flows in Low-Entropy Complex Systems

open access: yesEntropy, 2015
Nature’s many complex systems—physical, biological, and cultural—are islands of low-entropy order within increasingly disordered seas of surrounding, high-entropy chaos.
Eric J. Chaisson
doaj   +1 more source

Bone Mineral Density Evolution and Its Determinants in Long-term Survivors of Childhood Acute Leukemia: A Leucémies Enfants Adolescents Study. [PDF]

open access: yesHemasphere, 2021
Tabone MD   +18 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Evolution of density structures in the inner magnetosphere using coordinated Van Allen probe observations

open access: yesFrontiers in Astronomy and Space Sciences
The plasmasphere contains rich small-scale structure that plays a key role in regulating wave propagation and mass transport in the inner magnetosphere, yet the evolution of plasmaspheric density ducts remains poorly understood. We use joint observations
Tyler Bishop, Lauren Blum
doaj   +1 more source

Home - About - Disclaimer - Privacy