Results 71 to 80 of about 923,096 (261)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Silt Density Index

open access: yes
Abstract The most widely accepted and historically used predictor of the fouling potential of reverse osmosis feedwater is the plugging factor (PF), now commonly known as the Silt Density Index (SDI). The SDI procedure was standardized by ASTM International and is intended to be used as a measure of the fouling capacity of feedwater to ...
openaire   +1 more source

Soil compaction in progressive agricultural tractor treads

open access: yesRevista Brasileira de Engenharia de Biossistemas
Soil compaction is one of the main problems in world agriculture. It is known that, even in soil conservation management, such as in no-till, the transit of agricultural machinery damages the soil structure, therefore, it is essential to better ...
Aldir Carpes Marques Filho   +4 more
doaj   +1 more source

Reduced neurite density index in the prefrontal cortex of adults with autism assessed using neurite orientation dispersion and density imaging. [PDF]

open access: yesFront Neurol, 2023
Arai T   +11 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

HIGH DENSITY REFRACTIVE INDEX OF XENON

open access: yesLe Journal de Physique Colloques, 1984
The refractive index of Xenon is determined over a large range of density (up to 0,06 mole cm-3). The Lorentz factor decreases strongly with increasing density. A critical discussion on Herzfeld criterion of metallization is made.
Itie, J., Le Toullec, R.
openaire   +2 more sources

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