Results 71 to 80 of about 923,096 (261)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Disparity in hospital beds' allocation at the county level in China: an analysis based on a Health Resource Density Index (HRDI) model. [PDF]
Wang Z, Dong L, Xing X, Liu Z, Zhou Y.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Abstract The most widely accepted and historically used predictor of the fouling potential of reverse osmosis feedwater is the plugging factor (PF), now commonly known as the Silt Density Index (SDI). The SDI procedure was standardized by ASTM International and is intended to be used as a measure of the fouling capacity of feedwater to ...
openaire +1 more source
Soil compaction in progressive agricultural tractor treads
Soil compaction is one of the main problems in world agriculture. It is known that, even in soil conservation management, such as in no-till, the transit of agricultural machinery damages the soil structure, therefore, it is essential to better ...
Aldir Carpes Marques Filho +4 more
doaj +1 more source
Reduced neurite density index in the prefrontal cortex of adults with autism assessed using neurite orientation dispersion and density imaging. [PDF]
Arai T +11 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
HIGH DENSITY REFRACTIVE INDEX OF XENON
The refractive index of Xenon is determined over a large range of density (up to 0,06 mole cm-3). The Lorentz factor decreases strongly with increasing density. A critical discussion on Herzfeld criterion of metallization is made.
Itie, J., Le Toullec, R.
openaire +2 more sources

