Results 181 to 190 of about 4,404,911 (264)

Natural Atomic Orbitals at the Complete-Basis-Set Limit: A Frozen Natural-Minimal-Basis Construction. [PDF]

J Comput Chem
Szczepanik DW.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A method for calculating wetting collapse potential of loess based on basic physical indices. [PDF]

iScience
Fan X, Shao C, Wang H, Song M, Ren C, Li L.   +5 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Entropic Dynamics of Jump-Diffusion Option Pricing. [PDF]

Entropy (Basel)
Abedi M.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Multiplayer social dilemmas in completely mixed populations and networks of mixing communities. [PDF]

J Math Biol
Pires DL, Broom M.
europepmc   +1 more source

Size, Shape, Density, and Atmospheric Limit of (50000) Quaoar Revealed from 14 years of Stellar Occultation [PDF]

G. Margoti, F. Braga-Ribas, José Luis Ortiz, B. Sicardy, J. Desmars, Bruno Eduardo Morgado, E. Gradovski, C. L. Pereira, P. Santos-Sanz, A. R. Gomes-Júnior, J. I. B. Camargo, M. Assafin, Roberto Vieira-Martins, Yucel Kilic, D. Souami, R. Duffárd, G. Benedetti-Rossi, Tiago F. L. L. Pinheiro, Maísa Poiani, Eduardo Rondón, Marcelo Emilio, David Herald, Rafael Sfair, Nicolás Morales, F. Colas, F. Vachier, Mónica Vara Lubiano, Rodrigo Boufleur, Mert Acar, F. J. Aceituno, M. R. Alarcón, Sinan Aliş, Sergio Alonso, J. Alonso-Santiago, Flavia Amadio, L. Andrade, Pascal André, Jonatã Arcas-Silva, Alper K. Ateş, David Lafuente Aznar, Michael Backes, M. N. Bagiran, Nelson Balcar, M. A. Barry, Khalid Barkaoui, W. Beisker, Kirk Bender, Z. Benkhaldoun, S. Boeva, Eberhard H. R. Bredner, Richard Busuttil, Artem Burdanov, Oscar Canales, Javier Zaragoza-Cardiel, V. Casanova, Matheus Leal Castanheira, Peter Ceravolo, Steven J. Conard, Luciano Negrello Correa, Daniel V. Cotton, V. S. Dhillon, Serena Diamond, Vlad Dumitrescu, Joan Dunham, David Dunham, Christopher L Duston, E. G. Elhosseiny, O. Erece, Sila Eryilmaz, Emilio Fernández-García, Süleyman Fişek, R. Scott Fisher, Clyde Foster, Eric Frappa, Antonio Frasca, Jonah Frey, José María Gómez-Limón Gallardo, Jose Luis Maestre Garcia, D. Gault, K. Gazeas, Kai Getrost, M. Gillon, Alan Gilmore, Robert Glassey, Bruce Gowe, K. D. Green, William Hanna, Nicholas J. Haigh, Dean Hooper, K. Hornoch, Dragana Ilić, Cristóvão Jacques, F. Jankowsky, Emmanuël Jehin, Selami Kalkan, Roxanne L. Kamin, M. K. Kamińska, S. Kaspi, J. J. Kavelaars, Stephen Kerr   +99 more
openalex   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Refractory to Improvement: A Cautionary Tale of Two-Electron Densities Computed with One-Electron Basis Sets and of Their Employment in Quantum-Chemical Formalisms. [PDF]

J Chem Theory Comput
Cioslowski J, Domin J, Matito E.
europepmc   +1 more source