Results 251 to 260 of about 4,404,911 (264)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Allee Effect and Oncolytic Virotherapy: Different Therapeutic Outcomes for Different Tumour Growth. [PDF]

Bull Math Biol
Chen J, Frascoli F, Zhang T.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Graphene-nanodiamond membranes for atomic-impact sensing: design and fluorescence readout limits. [PDF]

Nanoscale Adv
Fiedler J, Eder SD, Zalieckas J.
europepmc   +1 more source

Designing next-generation non-linear optical crystals: polar chalcopyrite Li₂PbGeS₄ with a large NLO response, birefringence and microscopic first hyperpolarizability: a density functional calculation. [PDF]

RSC Adv
Reshak AH.
europepmc   +1 more source

Development of a Three-Component Nutrient Density Calculator (NDC) for Mixed Dishes to Guide Innovation and Reformulation of Recipes. [PDF]

Nutrients
Maillot M, Calabretta V, Schulz J, Bonnema A, Drewnowski A.   +4 more
europepmc   +1 more source

Strength behaviour of Clayey Soil modified with processed periwinkle shell ash. [PDF]

Sci Rep
Assam SA, Agunwamba JC, Akpabio MU.
europepmc   +1 more source

Natural Selection as a Process That Increases Metabolic Entropy Production? A Regime-Dependent Analysis in Open Chemostat Systems with Michaelis-Menten Kinetics and Mutation-Selection Dynamics. [PDF]

Entropy (Basel)
Gioia L.
europepmc   +1 more source