Results 161 to 170 of about 1,135,168 (297)

Quantifying single-cell responses to irradiation in 3D. [PDF]

Front Bioeng Biotechnol
François J, Simerzin A, Jambhekar A, Lahav G.   +3 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Tau oligomerization induces nuclear lamina invagination and chromatin remodeling in Alzheimer's disease. [PDF]

Acta Neuropathol
Yuan S, Essepian N, Roberts R, Sherman E, Wang Q, Erisir A, Jiang L.   +6 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Morphofunctional Heterogeneity and Plasticity of Glioblastoma Cells Induced to Senescence by Temozolomide. [PDF]

Aging Cell
da Rosa SA, de Oliveira HQ, de Mendonça LB, de Oliveira NB, Jaeger MDC, Pereira LC, Oliveira FDP, Santos-Sousa D, Saez-Calazans F, Lenz L, Lakadamyali M, Lenz G, Filippi-Chiela EC.   +12 more
europepmc   +1 more source

Role of Shell Model Nuclear Level Densities for Nuclear Astrophysics [PDF]

Proceedings of 11th Symposium on Nuclei in the Cosmos — PoS(NIC XI), 2011
Mihai Horoi, Roman Senkov
openaire   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Neuronal activity drives PCDH9 cleavage and nuclear translocation to coordinate structural and functional remodeling. [PDF]

Front Cell Neurosci
Miozzo F, Zambrano Avendano A, Caso MG, Valentino B, Hirano S, Murru L, Moretto E, Passafaro M.   +7 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Combined Burst Mode versus Torsional Mode Phacoemulsification for Patients with Hard Nuclear Cataracts: A Prospective Comparative Cohort Study. [PDF]

Clin Ophthalmol
Ainiwaer M, Hong Y, Xiao B, Sun Y, Zhang S, Ning L, Liu H, Zhu X, Ji Y.   +8 more
europepmc   +1 more source