Results 171 to 180 of about 543,786 (314)

A simple morphometric algorithm based on nuclear atypia features of invasive breast carcinoma: relationship with nuclear grade, Ki-67 level, and hormone receptor status. [PDF]

Breast Cancer
Tsuru T, Watanabe T, Kouzu K, Yamagishi Y, Einama T, Yamasaki T, Tsujimoto H, Kishi Y, Ueno H, Tsuda H.   +9 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Nrf2 mRNA in the first trimester as a predictive biomarker for gestational diabetes mellitus. [PDF]

Endocr Connect
Zhong X, Li S, Liu X, Li Q, Shen P.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The importance of parity-dependence of the nuclear level density in the prediction of astrophysical reaction rates

, 2003
A simple description for obtaining the parity distribution of nuclear levels in the pf + g(9/2) shell as a function of excitation energy was recently derived. We implement this in a global nuclear level density model.
Mocelj, D., Rauscher, T., Martinez-Pinedo, Gabriel, Alhassid, Y.   +3 more
core  

Multimodal evaluation of 525 nm laser-induced retinal injury in rabbits: structural, functional and cytokine analyses. [PDF]

Lasers Med Sci
Guo L, Chen K, Li G, Zeng J, Fan Z, Li C, Zou Y, Xu J, Zhang J.   +8 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Stretch regulated surface roughness controls macrophage inflammatory polarization through adhesion-chromatin coupling. [PDF]

Front Pharmacol
Yang G, Han Y, Tang T, Liu X, He HY, Xiong YF, Wang JW, Qing XS, Zhang C.   +8 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Retinal and Optic-Disc Changes Associated With ¹³¹I Therapy in Papillary Thyroid Carcinoma and Their Determinants. [PDF]

Invest Ophthalmol Vis Sci
Li YJ, Hu D, Feng HT, Zhang ZY, Yang ZA, Wang YX, Liu TY, Li SJ, Liu HY.   +8 more
europepmc   +1 more source