Results 91 to 100 of about 7,577,391 (289)

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

Age estimation and pedopornography

open access: yes, 2007
The presentation aims at exposing the difficulties which may be encountered in cases of age estimation from pedopornographic ...
C. Cattaneo
core   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

open access: yesAdvanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng   +15 more
wiley   +1 more source

Assessment of dental age estimation methods applied to Indian population: a systematic review

open access: yes, 2021
Forensic age estimation is a scientific process that estimates an individual's true chronologic age by assessing skeletal and dental development and maturation.
Maria Tereza Campos Vidigal   +2 more
core   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

open access: yesAdvanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong   +5 more
wiley   +1 more source

Dental age estimation from panoramic X-ray images using statistical models

open access: yes, 2017
This paper presents an application of computer vision methods to dental age estimation based on the lower third right molar in panoramic X-ray images. For this purpose, two statistical computer vision models are adjusted and applied: Active Shape Model ...
Vodanović, Marin   +11 more
core   +1 more source

Are the international dental age estimation methods accurate in African populations? A systematic review

open access: yes, 2021
Forensic age estimation is a scientific process that estimates an individual's true chronologic age by assessing skeletal and dental development and maturation.
Murilo Oliveira   +2 more
core   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

open access: yesAdvanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore   +6 more
wiley   +1 more source

Dental Age Estimation in Children Using Orthopantomograms

open access: yesActa stomatologica Croatica, 2008
Developing teeth are used to assess maturity and estimate age in a number of disciplines, such as pediatric and preventive dentistry, orthodontics, forensic odontology, etc. The accuracy of different methods has not been systematically investigated within the Croatian population, so the aim of this investigation was to determine the accuracy of two ...
Sever Nina   +3 more
openaire   +3 more sources

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