Survival Rates of Teeth with Primary Endodontic Treatment after Core/Post and Crown Placement [PDF]
Introduction The objective of this study was to determine the effect of delayed placement of the core/post and crown on the outcomes of nonsurgical root canal therapy (NSRCT).
Barkley, Gordon L., III +6 more
core +1 more source
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang +9 more
wiley +1 more source
A Model for the Analysis of Caries Occurrence in Primary Molar Tooth Surfaces [PDF]
Recently methods of caries quantification in the primary dentition have moved away from summary ‘whole mouth’ measures at the individual level to methods based on generalised linear modelling (GLM) approaches or survival analysis approaches. However, GLM
Baelum V +29 more
core +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Digital Panoramic Radiography in Dental Age Estimation
The present study aimed to assess the validity of coronal pulp/tooth area ratio (AR) and tooth/coronal index (TCI) indices in the mandibular first molar and second premolar for age estimation.110 digital panoramic radiographs of 60 male and 50 female subjects aged between 15 to 44 years were studied.
openaire +1 more source
Deciduous enamel 3D microwear texture analysis as an indicator of childhood diet in medieval Canterbury, England [PDF]
This study conducted the first three dimensional microwear texture analysis of human deciduous teeth to reconstruct the physical properties of medieval childhood diet (age 1-8yrs) at St Gregory's Priory and Cemetery (11th to 16th century AD) in ...
Deter, Chris +7 more
core +3 more sources
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Dental Radiograph: Tool for Age Estimation [PDF]
Sunit Patel +3 more
openaire +1 more source
Cephalometric studies of the mandible, its masticatory muscles and vasculature of growing Göttingen Minipigs — A comparative anatomical study to refine experimental mandibular surgery [PDF]
Over many decades, the Göttingen Minipig has been used as a large animal model in experimental surgical research of the mandible. Recently several authors have raised concerns over the use of the Göttingen Minipig in this research area, observing ...
Corte, Guiliano Mario +4 more
core +3 more sources
Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin +15 more
wiley +1 more source

