Results 151 to 160 of about 17,433 (282)

Ancient dental calculus reveals oral microbiome shifts associated with lifestyle and disease in Great Britain. [PDF]

Nat Microbiol, 2023
Gancz AS, Farrer AG, Nixon MP, Wright S, Arriola L, Adler C, Davenport ER, Gully N, Cooper A, Britton K, Dobney K, Silverman JD, Weyrich LS.   +12 more
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Extraction Protocol for Parallel Analysis of Proteins and DNA from Ancient Teeth and Dental Calculus. [PDF]

J Proteome Res, 2023
Chocholova E, Roudnicky P, Potesil D, Fialova D, Krystofova K, Drozdova E, Zdrahal Z.   +6 more
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Beyond dirty teeth: Integrating dental calculus studies with osteoarchaeological parameters. [PDF]

Quat Int, 2023
Radini A, Nikita E.
europepmc   +1 more source

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

Aragonite toothpaste for management of dental calculus: A double-blinded randomized controlled clinical trial. [PDF]

Clin Exp Dent Res, 2022
Al-Hashedi AA, Dubreuil N, Schwinghamer T, Dorzhiyeva S, Anweigi L, Emami E, Tamimi F.   +6 more
europepmc   +2 more sources

Insights into demographic and cultural influences on the oral microbiome from historical Japanese dental calculus. [PDF]

Sci Rep
Kuriyama Y, Mizuno F, Yamada T, Kumagai M, Tanaka M, Naka I, Hirata K, Mizushima S, Yonemoto S, Funahashi K, Seguchi N, Sakaue K, Kanazawa E, Matsushita M, Matsushita T, Saso A, Nara T, Sawaura R, Katagiri C, Maekawa T, Kurosaki K, Saitoh H, Namiki S, Ueda S, Ohashi J.   +24 more
europepmc   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Dental Calculus Deposition: Correlation With Salivary Statherin and Calcium Levels. [PDF]

Int J Dent
Hase P, Shah V, Gunjal S, Manjunatha BS, Pateel DGS.   +4 more
europepmc   +1 more source