Results 41 to 50 of about 14,573 (248)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Advances and challenges in periodontal disease inequalities in Brazil: a population-based comparative analysis, 2010-2023 [PDF]

Revista Brasileira de Epidemiologia
Objective: To analyze the prevalence of gingival bleeding, dental calculus, and shallow and deep periodontal pockets in the Brazilian National Oral Health Survey (SB Brasil) 2010 and 2023, and to examine their association with socioeconomic determinants.
Lívia Valéria Lins e Silva, Bruno Ferraz Barbosa da Costa, Edson Hilan Gomes de Lucena, Yuri Wanderley Cavalcanti, Sabrina Garcia de Aquino   +4 more
doaj   +4 more sources

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Dental Calculus Formation Is Linked to Diet and Phylogeny in Mammals

Ecology and Evolution
The oral microbiome is implicated in a wide diversity of fundamental biological functions, with the oral cavity serving as a connection between the host and the external environment.
John L. Richards, Markella Moraitou, Ella Nates, Konstantina Saliari, Emmanuel Gilissen, Zena Timmons, Andrew C. Kitchener, Olivier S. G. Pauwels, Richard Sabin, Phaedra Kokkini, Roberto Portela Miguez, Katerina Guschanski   +11 more
doaj   +1 more source

Emerging technologies for dental calculus detection and their clinical applications

Kouqiang hemian waike zazhi
Dental calculus is a significant contributor to periodontal disease, making its accurate identification crucial for effective prevention and treatment. Traditional methods for identifying dental calculus have the problems of strong subjectivity and low ...
ZHANG Longjie, WANG Xuquan, ZHOU Min
doaj   +1 more source

Extrusion‐Based Additive Manufacturing of Advanced Ceramics: Strengthening Mechanisms and Process Optimization Review

Advanced Engineering Materials, EarlyView.
This review comprehensively evaluates extrusion‐based additive manufacturing for advanced ceramics, detailing feedstock options and key process parameters. By critically addressing defect mechanisms like porosity and cracking, the work highlights optimization strategies through machine learning and advanced postprocessing.
Meisam Bakhtiari, Mohammad Hadi Sheikh‐Ansari, Avinash Borgaonkar, Mehran Dadkhah, Abdollah Saboori   +4 more
wiley   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Dental Calculus – An Evergrowing Heap of Periodontal Pathogens

Journal of Integrated Health Sciences, 2019
Dental calculus is defined as an adherent, calcified, or calcifying mass that forms on the surface of teeth and dental appliances. Calculus plays a key role in maintaining and accentuating periodontal disease by withholding the plaque in close contact ...
Kevin Saraiya, Prasad Nadig, Monali Shah, Deepak Dave   +3 more
doaj   +1 more source

Dental caries level among patients attending dental clinics complex at King Faisal University, Saudi Arabia: A retrospective study

Saudi Journal of Oral Sciences, 2023
Introduction: Dental caries or tooth decay is one of the most prevalent chronic diseases in adults and children worldwide, as it affects 60–90% of school-aged children and the vast majority of adults, and it is the primary cause of pain and tooth loss in
Elwalid Fadul Nasir
doaj   +1 more source