Results 61 to 70 of about 47,132 (294)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Emerging technologies for dental calculus detection and their clinical applications
Kouqiang hemian waike zazhiDental calculus is a significant contributor to periodontal disease, making its accurate identification crucial for effective prevention and treatment. Traditional methods for identifying dental calculus have the problems of strong subjectivity and low ...
ZHANG Longjie, WANG Xuquan, ZHOU Min
doaj +1 more source
Saudi Journal of Oral Sciences, 2023 Introduction: Dental caries or tooth decay is one of the most prevalent chronic diseases in adults and children worldwide, as it affects 60–90% of school-aged children and the vast majority of adults, and it is the primary cause of pain and tooth loss in
Elwalid Fadul Nasir
doaj +1 more source
Paleoamerican diet, migration and morphology in Brazil [PDF]
, 2011 During the early Holocene two main paleoamerican cultures thrived in Brazil: the Tradição Nordeste in the semi-desertic Sertão and the Tradição Itaparica in the high plains of the Planalto Central.
Eggers, Sabine +3 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Dental Calculus – An Evergrowing Heap of Periodontal Pathogens
Journal of Integrated Health Sciences, 2019 Dental calculus is defined as an adherent, calcified, or calcifying mass that forms on the surface of teeth and dental appliances. Calculus plays a key role in maintaining and accentuating periodontal disease by withholding the plaque in close contact ...
Kevin Saraiya +3 more
doaj +1 more source
The oral microbiome and adverse pregnancy outcomes. [PDF]
, 2017 Significant evidence supports an association between periodontal pathogenic bacteria and preterm birth and preeclampsia. The virulence properties assigned to specific oral pathogenic bacteria, for example, Fusobacterium nucleatum, Porphyromonas ...
Angolkar, Mubashir +5 more
core +3 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Gingival Recession, Oral Hygiene and Associated Factors Among Tanzanian Women. [PDF]
, 2009 Females are generally more motivated with regard to oral hygiene practices and thus brush their teeth more frequently than males. To determine the prevalence of gingival recession, oral hygiene status, oral hygiene practices and associated factors in ...
Honkala, E +3 more
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