Results 91 to 100 of about 4,522,408 (256)

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Dental utilisation by young adults before and after subsidisation reform in Finland [PDF]

open access: yes
Dental care was never fully integrated into the welfare state in Finland, but in 1986 it was decided to improve access to both publicly and privately provided dental care by reducing the price paid by patients. Since this would have been rather expensive
Gunnar Rosenqvist   +2 more
core  

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Clinical dental care in hospital dental departments in Taiwan: Results from the 2008 national survey

open access: yes, 2017
Background/purpose: Hospital accreditation in Taiwan was begun in 1978, but dental departments were not included until much later. In 2007-2008, a field survey of dental departments of hospitals was carried out.
林俊彬   +1 more
core   +1 more source

The relationship of dental caries and dental fear in Malaysian adolescents: a latent variable approach [PDF]

open access: yes, 2014
This paper is funded by University Malaya.Background To investigate the role of geography (place of residence) as a moderator in the relationship between dental caries disease and treatment experience and dental fear in 16-year-olds living in Malaysia ...
Humphris, Gerry   +10 more
core   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

Provision of dental care for special care patients: the view of Irish dentists in the Republic of Ireland. [PDF]

open access: yes, 2010
Part 2 of the Disability Act 2005 requires that all people with a disability are entitled to a needs assessment and, by implication, provision of identified care needs.
Nunn, J, Smith, G, Rooney, Y
core  

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