Results 71 to 80 of about 243,623 (266)

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Access to Dental Care for Children and Young People in Care and Care Leavers: A Global Scoping Review

Dentistry Journal
Aims: This scoping review aimed to explore three research questions: 1. What is the dental care access for children and young people (CYP) in care and care leavers? 2. What factors influence CYP in care and care leavers’ access to dental care? 3.
Jo Erwin, Jane Horrell, Hannah Wheat, Nick Axford, Lorna Burns, Joelle Booth, Robert Witton, Jill Shawe, Janine Doughty, Sarah Kaddour, Skye Boswell, Urshla Devalia, Abigail Nelder, Martha Paisi   +13 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Dental Care Use Among Pregnant Women in the United States Reported in 1999 and 2002

Preventing Chronic Disease, 2005
Introduction The purpose of this study was to determine national and state-specific estimates of dental care use among adult pregnant women in the United States using data from two 12-month periods. The study also determined person-level characteristics
Peggy Timothé, DDS, MPH, Paul I. Eke, PhD, MPH, PhD, Scott M. Presson, DDS, MPH, Dolores M. Malvitz, DrPH   +3 more
doaj  

Accessibility of Patients With Special Healthcare Needs to Dental Care in the Eastern Province of Saudi Arabia: A Multicentre Study From Perspective of Caregiver and Dental Care Providers

The Scientific World Journal
Dental care accessibility is subject to a dentist’s qualification, practice and intention to treat patients, regardless of whether those patients have special healthcare needs (SCN) and should receive treatment in a dental setting. This multicentre study
Tarek Ezzeldin, Mazin Algahtani, Nadia Abdulrahman Alghannam, Faisal Abdulkareem Alsafran, Intisar Ahmad Siddiqui, Hebah Zaki Al-Ghanim, Basma Mohamed Bader, Abdullah Abdulatif Alshubat, Adnan Hamad Almarry, Hussein Hejji IbnAhmed, Sarah Abdulhadi Kanakri, Reem Babiker Eltayeb, Mohammed Ibrahim Almuaybid, Khalaf Ali Al-Wasi   +13 more
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Patient Perspective on Dental Care Amidst COVID-19 Pandemic: A Survey During Omicron Stage

Journal of Patient Experience
The COVID-19 pandemic influenced dental care behaviors, with increased concern over virus transmission. This study provides insights into Thai patient behaviors and attitudes about dental care during the Omicron wave.
Paratcha Pingsuthiwong DDS, MSc, Paswach Wiriyakijja DDS, MSc, PhD, Pagaporn Pantuwadee Pisarnturakit DDS, PhD, Keskanya Subbalekha DDS, PhD   +3 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source