Results 101 to 110 of about 237,631 (316)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Condições de saúde bucal e capacidade funcional em idosos: um estudo longitudinal de base populacional

Revista Brasileira de Epidemiologia
RESUMO: Introdução: O estudo das condições de saúde bucal em idosos, aliado à busca de uma associação com a sua capacidade funcional, representa um importante passo para auxiliar na compreensão dos fatores intervenientes no cuidado odontológico desses ...
Yan Nogueira Freitas, Kenio Costa Lima, Diviane Alves da Silva   +2 more
doaj   +1 more source

The impact of out-of-pocket payments for dental care on household finances in low and middle income countries

BMC Public Health, 2017
Background Dental care is extremely costly and beyond most people means in developing countries. The primary aim of this study was to determine the impact of out-of-pocket payments for dental care on household finances in 40 low and middle income ...
Eduardo Bernabé, Mohd Masood, Marko Vujicic   +2 more
doaj   +1 more source

Geographical patterns of unmet health care needs in Italy [PDF]

In recent years, health care reforms and restrained budgets have risen concerns about accessibility to health services, even in countries with universal coverage health systems.
Cavalieri, Marina
core   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Fatores associados à satisfação com serviços odontológicos entre idosos

Revista de Saúde Pública
OBJETIVO: Analisar a prevalência da satisfação de idosos com o atendimento odontológico e os fatores associados. MÉTODOS: Estudo transversal com 495 idosos de 65 a 74 anos, sem déficit cognitivo, conforme miniexame do estado mental, que usaram serviços ...
Carlos Alberto Quintão Rodrigues, Paula Luciana Veloso Silva, Antônio Prates Caldeira, Isabela Almeida Pordeus, Raquel Conceição Ferreira, Andréa Maria Eleutério de Barros Lima Martins   +5 more
doaj  

Multimorbidity patterns and prevalence among geriatric patients in Japanese hospital dentistry

BMC Geriatrics
Background This study aimed to determine the prevalence of multimorbidity of a hospital dental patients with high rates of aging in Japan and to identify multimorbidity patterns in older patients (aged 65 years and older) through cluster analysis. As the
Kousuke Matsumoto, Takako Tsutsui, Ryu Hashimoto, Mitsuaki Sakakura, Tetsuari Onishi, Masaya Akashi   +5 more
doaj   +1 more source

Oral Health Services in Long-term Care Facilities Between 1989 and 2003—Has Germany Seen any Progress?

International Journal of Gerontology, 2011
Background: In view of the growing number of people requiring long-term nursing care the problem of dental care in long-term care facilities (LTCFs) remains an open issue.
Ina Schumann, Bernhard Albert Johannes Sobotta, Thomas Reiber, Ina Nitschke   +3 more
doaj   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source