Results 61 to 70 of about 94,461 (309)

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

open access: yesAdvanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar   +6 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

A Comparison of Pain Perception and Efficiency in NumBee versus Conventional Injection [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Background and Objective: The pain and anxiety caused by ordinary dental syringes in children has led to the invention of needle-free injection, which can affect the attitude of young patients towards dentistry.
D Kamal Naji, Z Juma Jafar, B Ahmed Yas
doaj  

Micro-Morphological Features of the Er:YAG-Lased Interface in Primary Teeth: 12 Months Randomized Split-Mouth Trial

open access: yesJournal of Functional Biomaterials
Despite considerable improvements in oral health, dental caries remains a public health issue. The most frequently used technique to remove caries is through rotating drills. New minimally invasive strategies were introduced into dental practice, such as
Osama Felemban   +5 more
doaj   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang   +14 more
wiley   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

NEW APPROACHES TO STOMACH CANCER PREVENTION IN VIEW OF PERIODONTAL STATUS OF PATIENTS

open access: yesКреативная хирургия и онкология, 2017
Patients with gastric  ulcer, associated with Helicobacter pylori infection, have passed dental  examination and  gingivitis  and  periodontal treatment with  usage  of  lyophilized kumyss lactic acid bacillus and bismuth preparation. Measure time course 
S. V. Chuykin, T. V. Bashirova
doaj   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

open access: yesAdvanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang   +25 more
wiley   +1 more source

A 12-month Follow-Up Study of Pulp Oxygen Saturation in Deciduous Molars After Selective and Nonselective Carious-Tissue Removal: A Randomized Pilot Trial

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2023
Objective: To compare the pulp vitality of deciduous molars before and after selective caries removal (SCR) or nonselective caries removal to hard dentin (NSCR) over one year, using oxygen saturation percentage (%SaO2).
Pierre Adriano Moreno Neves   +5 more
doaj  

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