Results 111 to 120 of about 1,102,634 (373)

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

open access: yesAdvanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller   +3 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie   +18 more
wiley   +1 more source

A Systematic Review of Screw versus Cement-Retained Fixed Implant Supported Reconstructions

open access: yesClinical, Cosmetic and Investigational Dentistry, 2020
Mohamed Tharwat Hamed, 1 Hisham Abdullah Mously, 2 Saeed Khalid Alamoudi, 3 Abou Bakr Hossam Hashem, 4 Ghada Hussein Naguib 5 1Department of Oral & Maxillofacial Prosthodontics, King Abdulaziz University Faculty of Dentistry, Jeddah, Saudi Arabia ...
Hamed MT   +4 more
doaj  

Surface hardness of CEM cement and cold ceramic cement across different pH settings [PDF]

open access: yesJournal of Dental Materials and Techniques
Objective: This study aimed to assess the surface microhardness of calcium-enriched mixture cement (CEM) and cold ceramic (CC) cement after being cured in environments with different pH values.Methods: Sixty maxillary canines were obtained.
Maryam Kazemipoor, Rezvan Hosseini
doaj   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Dental and composite resin discoloration induced by different hydraulic calcium silicate-based cements: two-year in vitro assessment

open access: gold, 2023
Lucas Santos de JESUS   +9 more
openalex   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

open access: yesAdvanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao   +15 more
wiley   +1 more source

Retentiveness of implant-supported metal copings using different luting agents

open access: yesDental Research Journal, 2012
Background: With regard to potential retrievability of cement-retained implant restorations, the retentive strength of the luting agents is critical.
Farahnaz Nejatidanesh   +3 more
doaj   +1 more source

Demonstration of metastable paragenesis in the process of solid phase interaction in the system of СаО – Al[2]O[3] – SiO[2] [PDF]

open access: yes, 2012
A short characteristic of new type of foreign dental cements Mineral Trioxide Aggregate (MTA) for root canal dressing is presented. The results of experimental researchesdealing with the development of the composition and method of producing of the ...
Kuzmenkov, M. I.   +3 more
core  

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