Results 71 to 80 of about 1,655,272 (299)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Avaliação da infiltração marginal em restaurações de resina composta fotoativadas sob alta potência [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Introdução:técnicas restauradoras mais rápidas e efetivas são desejadas pela classe odontológica e alvo de muita investigação, levando ao constante ...
Medeiros, Caroliny Cabral
core  

Improving mechanical properties of flowable dental composite resin by adding silica nanoparticles [PDF]

Vojnosanitetski Pregled, 2013
Background/Aim. The main drawback of flowable dental composite resin is low strength compared to conventional composite resin, due to a low amount of filler, neccessary for achieving low viscosity and ease of handling.
Baloš Sebastian, Pilić Branka, Petronijević Branislava, Marković Dubravka, Mirković Siniša, Šarčev Ivan   +5 more
doaj   +1 more source

Generation of Nasal Cell‐Derived Human Alveolar Organoids and Organoid‐Macrophage Assembloids for in Vitro Lung Modeling

Advanced Science, EarlyView.
This study demonstrates the generation of human alveolar organoids from nasal cells, which, when co‐cultured with monocyte‐derived macrophages, promotes maturation of both components and forms alveolar assembloids resembling native alveoli. These alveolar organoids and assembloids offer accessible, physiologically relevant in vitro systems for ...
Man Chun Chiu, Shuxin Zhang, Cun Li, Yifei Yu, Zhixin Wan, Jingjing Huang, Wei Xue, Ying Zhou, Xiaoxin Zhu, Qiaoshuai Lan, Jiali Wu, Zijun Zhao, Yuhong Liu, Xinjie Meng, Lin Huang, Hin Chu, Honglin Chen, Kelvin Kai‐Wang To, Kwok Yung Yuen, Jie Zhou   +19 more
wiley   +1 more source

Immediate versus water-storage performance of Class V flowable composite restoratives [PDF]

, 2006
Objectives The aims of this investigation were to clarify the effects of 24 h water-storage and finishing time on mechanical properties and marginal adaptation to a Class V cavity of eight modern flowable resin-composites.
Hatanaka, Kenji, Suzuki, Kazuomi, Watts, David C., Watts, David C.; id_orcid, Irie, Masao   +4 more
core   +1 more source

Chemical Stability of Bioglass in Simulated Oral Environment

Journal of Dental Biomaterial, 2016
Statement of Problem: Bioglasses are a series of biocompatible dental materials, which are considered as light conducting inserts in resin composite restorations.
Moazzami SM, Sadid Zadeh R, Kianoush K, Sarmad M, Barani Karbaski F, Amiri Daluyi R, Kazemi RB   +6 more
doaj  

Management of anterior crossbite in mixed dentition using sloped composite resin: a case report

Padjadjaran Journal of Dentistry
Introduction: Dental-type anterior crossbite is a malocclusion involving an individual tooth, in which the maxillary incisor is positioned lingual to the mandibular incisor without skeletal discrepancy.
Devita Sanjaya, Sri Kuswandari
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Facetas: resinas ou cerâmicas? [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Neste trabalho, foi realizada uma revisão da literatura sobre facetas dentárias, com objetivo de comparar as vantagens e desvantagens das técnicas direta (
Biava, Carine
core  

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source