Results 151 to 160 of about 17,874 (251)

Rethinking Antibacterial Innovation in Dental Composites: Bridging Nanoparticle Design and Translational Potential. [PDF]

Int Dent J
Rattanapitoon SK, Chitpitaklert P, Srithongklang W, Rattanapitoon NK.   +3 more
europepmc   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Multiparametric performance comparison of dental composites for clear aligner attachments. [PDF]

BMC Oral Health
Guan Y, Xu J, Qiu J, Cai H, Xia W, Ye Z, Sang T.   +6 more
europepmc   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Silanised Fluoride Hydrotalcites as Functional and Multicomponent Fillers for Dental Composites. [PDF]

Biomimetics (Basel)
Nocchetti M, Piccinini M, Scafuri A, Di Michele A, Ambrogi V.   +4 more
europepmc   +1 more source

Sea Cucumber‐Inspired Double‐Network Biopolymer Hydrogels for Programmable Soft Machines

Advanced Science, EarlyView.
Inspired by the mutable dermis of sea cucumbers, the collagen‐alginate double‐network elastomeric (CoDE) hydrogel achieves programmable, recoverable, and functional mechanical behavior. The CoDE hydrogel mimics the mutable stiffness of the sea cucumber dermis through a densified collagen cryogel scaffold that is secondarily reinforced by a dissipative,
Luo Yan, He Xiao, Purohit Prashant K., Vining Kyle H.   +3 more
wiley   +1 more source

An <i>in vitro</i> evaluation of the effect of accelerated aging on the color stability and marginal adaptation of two single-shade dental composites. [PDF]

J Conserv Dent Endod
Dundage S, Kalasaiaha D, Mohan C, Narayana I, Shetty N, Ramesh P.   +5 more
europepmc   +1 more source

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

Advanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu, Meng Meng, Zhen‐Zhen Wang, Deng‐Lu Lu, Ya‐Min Wei, Xu‐Chang Mi, Xing‐Yu Mu, Wei Fu   +7 more
wiley   +1 more source

Relationship Between Fracture Toughness and Fracture Mirror in Modern Polymer-Based Dental Composites. [PDF]

J Funct Biomater
Ilie N.
europepmc   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source