Results 131 to 140 of about 525,663 (310)
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang +11 more
wiley +1 more source
Senior Dental Students’ Experience with Cariogram in a Pediatric Dentistry Clinic [PDF]
The study objective was to assess predoctoral dental students’ experience with a caries risk assessment computer program in the pediatric dentistry clinic at Marquette University School of Dentistry.
Gonzalez, Cesar, Okunseri, Christopher
core +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Community-based dental education in Iranian dental schools
Background Community-based dental education (CBDE) has been an essential advancement in dental education in recent decades, enhancing it in many aspects. This study aimed to determine the characteristics and improvements of CBDE in dental schools in Iran.
Ata Bandehagh +3 more
doaj +1 more source
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang +12 more
wiley +1 more source
The Dental Access Gap: Findings From a National Survey [PDF]
Presents findings about adults' access to dental care by income, race/ethnicity, dental insurance status, and education; reasons for delaying care; and views on the lack of affordable care and on dental therapy by licensed practitioners as an ...
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Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source
A needs and resource assessment approach to developing a comprehensive dental plan for Boston's Head Start program [PDF]
Thesis (M.Sc.)--Boston University, Henry M. Goldman School of Graduate Dentistry, 1979 (Dental Public Health).Includes bibliographical references: (leaves 49-50)
Project Head Start (US) +1 more
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