Results 231 to 240 of about 513,709 (334)

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

open access: yesAdvanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li   +13 more
wiley   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

open access: yesAdvanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim   +10 more
wiley   +1 more source

Challenges in dental education: A call for critical dialogue. [PDF]

open access: yesJpn Dent Sci Rev
Cassol Spanemberg J, Carrard VC.
europepmc   +1 more source

Dental Hygiene Education About Patients with Special Needs: A Survey of U.S. Programs [PDF]

open access: green, 2008
Maryam J. Dehaitem   +3 more
openalex   +1 more source

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