A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li +13 more
wiley +1 more source
Platelet-rich fibrin versus acellular dermal matrix for vertical soft tissue augmentation simultaneously with dental implantation: a 3-month randomized pilot clinical trial. [PDF]
Shiezadeh F +3 more
europepmc +1 more source
Effect of Anesthetics Containing Lidocaine and Epinephrine on Cardiovascular Changes During Dental Implant Surgery [PDF]
F Faraco +4 more
openalex +1 more source
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri +16 more
wiley +1 more source
Utilization of magnetic mallet during dental implantation in narrow mandibular alveolar ridge: A case report. [PDF]
Albassal A, Al-Khanati NM, Harfouch M.
europepmc +1 more source
Predicting Peri-implant Stresses Around Titanium and Zirconium Dental Implants—A Finite Element Analysis [PDF]
Manmohan Choudary Gujjarlapudi +5 more
openalex +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Immediate dental implantation after transcrestal sinus elevation by osseodensification in a severe atrophic alveolar ridge - Case report. [PDF]
Chen CC, Chang YC.
europepmc +1 more source

