Results 221 to 230 of about 43,526 (295)

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Hyperactivity is a persistent and clinically relevant symptom in anorexia nervosa (AN). Hyperactivity is inversely correlated with leptin levels. While systemic leptin administration attenuates hyperactivity in rodent models, the specific brain regions mediating this effect remain unclear.
Nick J. M. Papavoine, Melissa N. Veendijk, Jessie Nijman, Mieneke C. M. Luijendijk, Inge G. Wolterink‐Donselaar, Frank J. Meye, Roger A. H. Adan   +6 more
wiley   +1 more source

Computed tomography long‐term follow‐up of a facial fracture involving the orbit and paranasal sinus

Equine Veterinary Journal, EarlyView.
Abstract Background Fractures of the facial bones involving the orbit are challenging conditions that require surgical treatment. Objectives To describe preoperative and postoperative clinical and computed tomographic findings of an orbital rim fracture repaired using a reconstruction plate. Study Design Case report.
A. Kalinovskiy, C. Lischer, J. C. Eule, K. Thieme, K. Mählmann   +4 more
wiley   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Simultaneous Bi‐Jaw Reconstruction: Double Free Fibula Flap Following Resection of Synchronous Oral Malignancy

Head &Neck, EarlyView.
ABSTRACT Background Simultaneous reconstruction of extensive maxillary and mandibular defects in oncological cases is a complex surgical challenge. Methods We report a case of a 56‐year‐old female with synchronous oral malignancy involving upper and lower alveolus.
Subhendu Khan, Varun Saini, Vikram Singh, Ashish Gulia   +3 more
wiley   +1 more source

The Influence of Thrust Force on the Vitality of Bone Chips Harvested for Autologous Augmentation during Dental Implantation. [PDF]

Materials (Basel), 2019
Ben Achour A, Petto C, Meißner H, Hipp D, Nestler A, Lauer G, Teicher U.   +6 more
europepmc   +1 more source

Dental Rehabilitation of the Scapular Tip in Maxillary Reconstruction

Head &Neck, EarlyView.
ABSTRACT Introduction The fibula‐free flap has traditionally been utilized to perform dental rehabilitation following maxillectomy. The purpose of this study is to present our experience with dental implantation of the scapula–tip‐free flap in midface reconstruction.
Leba M. Sarkis, John Lee, Karl Cuddy, Brian Rittenberg, Majd Al Mardini, Christopher MKL Yao, Sharon Tzelnick, David Goldstein, Ralph Gilbert, John R. de Almeida   +9 more
wiley   +1 more source

Characterization of the Correct Mandibular Premolar Region for Delayed Dental Implantation in Beagle Dogs. [PDF]

J Am Assoc Lab Anim Sci, 2018
Xie C, Fu X, Xu L, Xu S.
europepmc   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source