Results 181 to 190 of about 811,330 (263)

Continuous local minocycline delivery from PLA nanosphere-coated dental implants with long-term antibacterial activity and biocompatibility. [PDF]

RSC Adv
Patiyananuwat N, Thanapongpibul C, Chinavinijkul P, Phumkrachai B, Ngamwongronnachai C, Tancharoen S, Nasongkla N.   +6 more
europepmc   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source

Long-Term Clinical and Radiographic Outcomes of Ceramic Dental Implants: An 11-Year Retrospective Cohort Study. [PDF]

J Esthet Restor Dent
Monzavi M, Masnavi M, Zraiqat A, Manesh A.   +3 more
europepmc   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Interaction between periodontal disease and colorectal cancer

EXCLI Journal : Experimental and Clinical Sciences
Thalles Yurgen Balduino, André Felipe dos Santos Teles, Gabriel Leonardo Magrin, Marco Aurélio Bianchini   +3 more
doaj   +1 more source

Overcoming the Biomechanical Limitations of Titanium-Zirconia Dental Implants: Rationale for a Novel Ti-PEEK-Zr Tri-Layered Concept. [PDF]

J Funct Biomater
Vacaru MC, Munteanu C, Lupu FC, Deleu G, Volocaru II, Earar K.   +5 more
europepmc   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Effects of UV Photo-Functionalization of Titanium Dental Implants on Osteoblast Responses In Vitro. [PDF]

Biomimetics (Basel)
Güçlü M, Tosun DA, Bağış N, Dastouri M, Can A, Karaaslan R.   +5 more
europepmc   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Root Canal Therapy Versus Single-Tooth Dental Implants for Compromised Teeth: A Retrospective Comparative Study. [PDF]

Cureus
Vijayan AA, Sarkar P, Madhuri BV, Kumar AV, Mohapatra A, Garain R, Ahmed MK.   +6 more
europepmc   +1 more source