Results 41 to 50 of about 154,856 (293)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Incorporation of disinfectants for obtaining dental stone: microbiological and dimensional evaluation

open access: yesRevista de Odontologia da UNESP
AIM: To assess dimensional change and antimicrobial activity of disinfectants substances incorporated during the dental stone manipulation. MATERIAL AND METHOD: In vivo - microorganisms were collected in alginate molds of 30 volunteers inoculated on BHI ...
Patrícia Lins Azevedo do Nascimento   +3 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Evaluation of biofilm colonization on multi-part dental implants in a rat model [PDF]

open access: gold, 2021
Eva Blank   +7 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Effect of different impression materials and techniques on the dimensional accuracy of implant definitive casts

open access: yesDental Research Journal, 2015
Background: Different factors such as impression techniques and materials can affect the passive fit between the superstructure and implant. The aim of this study was to determine the effect of different impression materials and techniques on the ...
Behnaz Ebadian   +3 more
doaj  

Influence of Different Post-Processing Procedures on the Accuracy of 3D Printed Dental Models Using Vat Polymerization: A Systematic Review

open access: yesApplied Sciences
Introduction: Three-dimensional (3D) printing technology has rapidly evolved across various fields of medicine and dentistry, particularly in orthodontics. One key application in orthodontics is the fabrication of dental models.
Athanasia Morali   +4 more
doaj   +1 more source

Dimensional accuracy of alginate mold method on duplication of stone casts

open access: yesCaspian journal of dental research, 2022
Introduction: Accurate duplication of casts is necessary to fabricate a proper prosthetic appliance with good adaptation. Alginate is an inexpensive impression material and is available in most dental offices. The aim of the present study was to evaluate
Neda Naderi Geisour   +4 more
doaj  

[Photoelastic models applied to dental restorations].

open access: yesRevista cientifica odontologica (Universidad Cientifica del Sur), 2021
Objetivo:  Mejorar la comprensión de los cambios generados por los procedimientos restaurativos a través de modelos fotoelásticos. La reconstrucción dental debe fundamentarse en principios de oclusión para no provocar puntos prematuros de contacto durante los procedimientso de preparación y restauración que pueden provocar transtornos como el ...
Marín-Miranda, Miriam   +2 more
openaire   +2 more sources

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