Results 91 to 100 of about 46,440 (282)

Accuracy of Dental Operating Microscope versus CBCT in detecting number of root canals for maxillary first molars indicated for retreatment

, 2023
One of the main causes of root canal treatment failure, whether primary treatment of retreatment is a practitioner’s inability to locate and disinfect all canals present in a root canal system.
Mostafa Sholkamy, Abeer H Mahran, Ahmed Abuelezz
core  

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

The application of dental microscope in root canal treatment and retreatment of maxillary first molar

口腔疾病防治, 2016
Objective To evaluatethe detection rate, typing, and therapeutic effect of second mesiobuccal canals(MB2) of first molars under dental operating microscope.Methods 88 maxillary molars with the presence of MB2 through cone beam computed tomography (CBCT ...
PENG Zheng-yu, HUANG Jie-ru, LI Zhi-fang, WEN Fei-li, MAI Sui   +4 more
doaj   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Indian Endodontic Society: Position statement on the management of separated instruments during root canal treatment

Endodontology
This position statement on the management of separated instruments, endorsed by the Indian Endodontic Society, aims to provide a brief perspective on the challenges faced during shaping of the complex root canal system, and how the inadvertent separation
Aishwarya Vasudevan, Sanjay Miglani, Vivek Hegde, Velayutham Gopikrishna   +3 more
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Metaseal Soft Paste Root Canal Obturation without GP.mp4

, 2023
Clinical video recording by dental operating microscope. Root canal obturation procedure using Metaseal Soft Paste without GP. 
Yuki Nishimura (165178), Koji Iwasaki (387364), Kiichi Moriyama (9634409), Masakatsu Watanabe (9634402), Mikako Hayashi (9634425), Motoki Okamoto (9634289), Kouki Nakatani (16032737), Saita Ryotaro (16032743), Sayako Matsumoto (9634406), Yusuke Takahashi (9634380)   +9 more
core   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Navigating and Managing Eight Canals in a Maxillary First Molar: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Understanding the existence of an additional root and atypical root canal anatomy is essential because it impacts the manner in which endodontic therapy occurs.
Harsha Nihalani, Anamika C Borkar, Soumya Sharath Shetty, Ajit Hindlekar, Komal Gupta   +4 more
doaj   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source