Results 91 to 100 of about 125,925 (352)
Parabiosis, Assembloids, Organoids (PAO)
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
Consideration for care for your patient with cerebral palsy [PDF]
Cerebral palsy (CP) is a common developmental neurological disorder affecting about 2-3 children out of 1,000. CP is the result of infant brain damage or abnormal development resulting in impaired muscle control, coordination, tone, reflex, posture, and ...
Cannon, Katlin R +2 more
core +1 more source
Fluoridated elastomers: effect on disclosed plaque [PDF]
OBJECTIVE: To investigate the effect of fluoridated elastomers on the quantity of disclosed dental plaque surrounding an orthodontic bracket in vivo.
Benson, P.E., Campbell, I.F., Shah, A.A.
core +1 more source
Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
wiley +1 more source
Periodontitis and the Elderly: An Overview of the Disease and its Impact on an Aging Population [PDF]
Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis ...
Weissenfluh, Nicole Grace
core +1 more source
The Mechanism and Potential Therapeutic Strategies of Vascular Aging
The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu +4 more
wiley +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Targeted antimicrobial therapy against Streptococcus mutans establishes protective non-cariogenic oral biofilms and reduces subsequent infection. [PDF]
AimDental biofilms are complex communities composed largely of harmless bacteria. Certain pathogenic species including Streptococcus mutans (S. mutans) can become predominant when host factors such as dietary sucrose intake imbalance the biofilm ecology.
Anderson, Maxwell +7 more
core +1 more source
This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding +7 more
wiley +1 more source
Objective: Confocal laser scanning microscopy (CLSM) is relatively a new light microscopical imaging technique with a wide range of applications in biological sciences. primary value of CLSM for the biologist is its ability to provide optical sections
KA. Al-Salihi +1 more
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