Results 171 to 180 of about 905,317 (350)

Aging Compromises Terminal Differentiation Program of Cytotoxic Effector Lineage and Promotes Exhaustion in CD8+ T Cells Responding to Coronavirus Infection

open access: yesAging Cell, EarlyView.
In a MHV infection model with age‐associated increased mortality, we demonstrate that aging impairs, instead of promoting, the terminal differentiation program of virus‐specific CD8+ T cells through downregulating key transcriptional regulators of terminal differentiation.
Ziang Zhu   +8 more
wiley   +1 more source

Comparative Evaluation of Natural Mouthrinses and Chlorhexidine in Dental Plaque Management: A Pilot Randomized Clinical Trial. [PDF]

open access: yesHealthcare (Basel)
Lile IE   +8 more
europepmc   +1 more source

Age‐Related Complement C3 Drives Memory Impairments and Associated Neuropathologies in a Mouse Model

open access: yesAging Cell, EarlyView.
Age‐related complement C3 elevation induces memory impairments and neuropathology by dysregulating astrocytic insulin signaling and triggering mitochondrial dysfunction. Critically, antibody blockade of C3 in mouse brain tissue effectively reversed learning and memory deficits in mice, demonstrating that targeting C3 is a promising therapeutic strategy.
Miaomiao Du   +10 more
wiley   +1 more source

Dental plaque-inspired peptide engineered to control plaque accumulation. [PDF]

open access: yesMater Today Bio
Wu H   +8 more
europepmc   +1 more source

The mechanism of dental plaque and dental calculus formation by fibronectin. 5. Adsorption of fibronectin onto hydroxyapatite in phosphate solution.

open access: bronze, 1986
Naoko HORADA   +8 more
openalex   +2 more sources

Impaired Cytokine Secretion Contributes to Age‐Dependent Immune Dysfunction in SARS Coronavirus Response and Is Restored by Young CD11b‐Positive Cell Transfer

open access: yesAging Cell, EarlyView.
Aged CD11b+ cells exhibit impaired IRF7 activation and reduced SNARE protein expression, leading to delayed interferon responses and diminished cytokine secretion. These dual deficits may contribute to the heightened susceptibility of older individuals to severe outcomes following SARS‐CoV infection.
Yu‐Xuan Wu   +10 more
wiley   +1 more source

The Probiotic Effects of Lactobacillus brevis CD2 on Caries Related Variables of Dental Plaque Biofilm. [PDF]

open access: yesInt Dent J
Campus G   +5 more
europepmc   +1 more source

Lactobacilli Isolation from Dental Plaque and Saliva of a Group of Patients with Caries and Characterization of their Surface Properties [PDF]

open access: green, 2001
Marı́a del Carmen Ahumada   +3 more
openalex   +1 more source

Oral Health Promotion Interventions in Residential Aged Care Facilities – A Systematic Review of Behaviour Change Techniques Used in Interventions

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Background The oral health status of older people living in residential aged care facilities (RACFs) is found to be very poor. Many oral health promotion interventions have been tested in RACF settings around the world with varying degrees of success.
Nesa Aurlene   +3 more
wiley   +1 more source

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