Results 51 to 60 of about 52,038 (309)

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Tooth brushing: An effective oral hygiene measure

Orapuh Journal, 2021
Many people adopt tooth brushing as their primary method of oral hygiene. Tooth brushing is a mechanical means of eliminating microbial biofilm (dental plaque) from the oral cavity. Evidences have shown that dental plaque is implicated in the initiation
Bemhemba Iba, VE ADAMU
doaj  

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source

Helicobacter pylori in the dental plaque of healthy Saudis

The Saudi Journal of Gastroenterology, 1998
The objective of this study is to determine the presence of Helicobacter pylori in the dental plaque of healthy Saudis and its relation to dental care.
Contractor Qais, Tahir Mohammed, Naseem Shahzad, Ahmad Shamweel   +3 more
doaj  

The Analysis of Dental Plaque Sections [PDF]

Microbial Ecology in Health & Disease, 1994
Dental plaque is a naturally occurring microbial layer or biofilm which develops on the tooth surface. l3 Its bacterial nature was first described by Antonie Van Leewenhoek in 169810 and research to date has demonstrated that it comprises bacteria in a matrix composed mainly of extracellular bacterial polymers and salivary/gingival fluid products ...
openaire   +2 more sources

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

Advanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu, Zhezhe Zhao, Xiang Liu, Jingrong Wang, Yufeng Zhang, Tingting Lan, Yonglan Wang, Chenxuan Wu, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Anjie Dong, Zujian Feng, Deling Kong, Weiwei Wang   +14 more
wiley   +1 more source

Current Approaches and Challenges in Advanced Oxidation Processes for Nanoplastic Degradation

Advanced Science, EarlyView.
This review explores recent progress in advanced oxidation processes (AOPs) for the degradation of nanoplastics (NPs) in water. It presents a comparative assessment of key AOP technologies and identifies current limitations in analytical methods and treatment efficiency.
Arezou Fazli, Athanassia Athanassiou, Despina Fragouli   +2 more
wiley   +1 more source

Elemental composition of solid dental deposits in patients with somatic pathology

Эндодонтия Today, 2019
For a number of systemic diseases accompanied by changes in the state of organs and tissues of the oral cavity, manifested more active over carious diseases, lesions of the oral mucosa and periodontal, dental plaque formation.
R. V. Polyakova, N. A. Nikolaev, V. B. Nedoseko   +2 more
doaj   +1 more source