Results 81 to 90 of about 127,508 (301)

Interkingdom interactions on the denture surface: implications for oral hygiene [PDF]

, 2019
Background: Evidence to support the role of Candida species in oral disease is limited. Often considered a commensal, this opportunistic yeast has been shown to play a role in denture related disease, though whether it is an active participant or ...
Alalwan, Allonsius, Beyer, Caporaso, Cho, Coco, Delaney, Gendreau, Hannah, Janus, Kean, Kean, Kong, Kozich, Kraneveld, Locker, Love, Mantzourani, Martori, Matsuda, McMurdie, Nunes, O'Donnell, O'Donnell, O'Donnell, O'Donnell, Offenbacher, Peric, Peters, Rajendran, Ramage, Ramage, Ramage, Sachdeo, Sherry, Sherry, Shi, Sztukowska, Teles, Yitzhaki   +39 more
core   +2 more sources

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Periodontitis and the Elderly: An Overview of the Disease and its Impact on an Aging Population [PDF]

, 2019
Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis ...
Weissenfluh, Nicole Grace
core   +1 more source

Respiratory pathogen colonisation of dental plaque, the lower airways and endotracheal tube biofilms during mechanical ventilation [PDF]

, 2017
Purpose In mechanically ventilated patients, the endotracheal tube is an essential interface between the patient and ventilator, but inadvertently, it also facilitates the development of ventilator-associated pneumonia (VAP) by subverting pulmonary host ...
Barnes, Rosemary A., Hayes, Anthony J., Lewis, Michael A. O., Palmer, Nicki, Sands, Kirsty M., Williams, David W., Wilson, Melanie J., Wise, Matt P.   +7 more
core   +1 more source

Dental plaque and gingival bleeding in adolescents with juvenile idiopathic arthritis and controls: a multilevel analysis [PDF]

, 2022
Elisabeth G. Gil, Anne Nordrehaug Åstrøm, Stein Atle Lie, Marite Rygg, Johannes Fischer, Annika Rosén, Athanasia Bletsa, Keijo Luukko, Xie‐Qi Shi, Josefine Halbig, Paula Frid, Lena Cetrelli, Karin Tylleskär, Karen Rosendahl, Marit Slåttelid Skeie   +14 more
openalex   +1 more source

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

How many times is the optimum dental floss frequency in people with normal ‎periodontium? A randomized controlled single blind clinical trial [PDF]

, 2015
BACKGROUND AND AIM: Due to the inadequate of a toothbrush in cleaning of interdental areas and further advanced developing of the disease in this area, dental flossing seems essential.
Hoda, Shamsaddin
core  

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source