Results 51 to 60 of about 120,768 (358)

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo

Journal of Translational Medicine
Background MicroRNAs (miRNAs) play a crucial role in cell differentiation through epigenetic regulation of gene expression. In human dental pulp cells, we have identified miRNA-27a being upregulated under inflammatory conditions.
Ziniu Yu, Nobuyuki Kawashima, Keisuke Sunada-Nara, Shihan Wang, Peifeng Han, Thoai Quoc Kieu, Chunmei Ren, Sonoko Noda, Kento Tazawa, Takashi Okiji   +9 more
doaj   +1 more source

Remineralization strategies in oral hygiene: a position paper of Italian Society of Oral Hygiene Sciences-S.I.S.I.O. working group [PDF]

, 2017
Background/Objective: The clinical conditions that lead to an alteration of the enamel structure are numerous. The diet high in sugars and acidifying substances, psychological stress that triggers parafunctional behaviors, the reduced intake of fiber ...
Acito, Giovanna, Bassignani, Jessica, Chiavistelli, Lorella, Cotellessa, Silvia, Fantozzi, Giulia, Iommiello, Alessia, Iommiello, Alessia, Nardi, Gianna Maria, Sabatini, Silvia, Sanavia, Consuelo, Tatullo, Marco   +10 more
core   +1 more source

RESUME OF THE HISTOLOGY OF THE DENTAL PULP. [PDF]

JAMA: The Journal of the American Medical Association, 1902
The consideration of the details of development and structure from a new point of view, I regret to say, is too incomplete and my opportunities have been too few to allow of the experimental work being completed in time for this meeting. I can only bring to your notice a number of what seem to me to be important questions bearing upon this subject for ...
openaire   +3 more sources

Biocompatible Multifunctional Polymeric Material for Mineralized Tissue Adhesion

Advanced Healthcare Materials, EarlyView.
A multifunctional thiol‐ene resin system is developed that provides a strong adhesive interface with dentin while maintaining biocompatibility with dental pulp cells. The addition of an acidic monomer to a triacrylate‐trithiol‐based resin achieves over 10 MPa shear bond strength by reinforcing the hybrid interface.
Yan Luo, Chenyang Zhang, Sage Fulco, Jingyi Liu, Keyu Chen, Yuntao Hu, Yuchen Jiang, Rui Xu, Leela Rakesh, Ozer Fusun, Ottman Tertuliano, Kevin Turner, Kyle H. Vining   +12 more
wiley   +1 more source

Early diagnosis of aortic calcification through dental X-ray examination for dental pulp stones

Scientific Reports, 2023
Vascular calcification, an ectopic calcification exacerbated by aging and renal dysfunction, is closely associated with cardiovascular disease. However, early detection indicators are limited.
Misao Ishikawa, Hiroyuki Kanzaki, Ryo Kodera, Takehiro Sekimizu, Satoshi Wada, Syunnosuke Tohyama, Tomomi Ida, Miho Shimoyama, Shugo Manase, Hiroshi Tomonari, Noriyuki Kuroda   +10 more
doaj   +1 more source

Outcomes of Primary Endodontic Therapy in Medicaid Enrollees [PDF]

, 2020
The objective of this study was to determine factors affecting survival of teeth after nonsurgical root canal therapy (NSRCT) among enrollees of Wisconsin Medicaid during the years 2001-2009.
Gainey, Timothy
core   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Effect of repetitive up-and-down movements on torque/force generation, surface defects and shaping ability of nickel-titanium rotary instruments: an ex vivo study

BMC Oral Health
Background The screw-in effect is a tendency of a nickel-titanium (NiTi) rotary endodontic file to be pulled into the canal, which can result in a sudden increase in stress leading to instrument fracture, and over-instrumentation beyond the apex.
Moe Sandar Kyaw, Arata Ebihara, Yoshiko Iino, Myint Thu, Keiichiro Maki, Shunsuke Kimura, Pyae Hein Htun, Takashi Okiji   +7 more
doaj   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source