Results 61 to 70 of about 823,715 (269)

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

Interdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang, Xiaoyu Ma, Ruiqi Gao, Qichen Miao, Guoqing Wang, Ziyuan Liu, Kun Wang, Ming Luo   +7 more
wiley   +1 more source

Multiple Pulp Stones in Primary and Developing Permanent Dentition: A Report of 4 Cases

Case Reports in Dentistry, 2012
Pulp stones are foci of calcification or discrete calcifications in the dental pulp. They are frequently found on bitewing and periapical radiographs, but their occurrence in entire dentition is unusual.
Mohita Marwaha, Radhika Chopra, Payal Chaudhuri, Atul Gupta, Jayna Sachdev   +4 more
doaj   +1 more source

Urethane dimethacrylate induces cytotoxicity and regulates cyclooxygenase-2, hemeoxygenase and carboxylesterase expression in human dental pulp cells

, 2017
The toxic effect of urethane dimethacrylate (UDMA), a major dental resin monomer, on human dental pulp is not fully clear. In this study, we investigated the influence of UDMA on the cytotoxicity, cell cycle distribution, apoptosis and related gene ...
Chang, Hsiao-Hua;Chang, Mei-Chi;Wang, Hsin-Hui;Huang, Guay-Fen;Lee, Yuan-Ling;Wang, Yin-Lin;Chan, Chiu-Po;Yeung, Sin-Yuet;Tseng, Shuei-Kuen;Jeng, Jiiang-Huei, 張曉華;黃桂芬;李苑玲;鄭景暉;王姻麟   +1 more
core   +1 more source

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Laura de Girolamo, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo   +8 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Association of pulp stones with coronary artery stenosis

, 2011
Background: Dental pulp stones are discrete calcifications in the pulp chamber which are often seen in deciduous and permanent teeth. It has been hypothesised that atherosclerosis can be associated with their development.
Sadr-Bafghi, S. M., Rahmani-Baghemalek, M. J., Hedayati, A. S., Ezoddini-Ardakani, F., Namayandeh, S. M., Fatehi, F., Mohammadi, Z., Shahrabi-Farahani, S.   +7 more
core   +1 more source

Body Size, Dental Pathology, and Maternal Genetic Diversity of Ancient Horses in the Eastern Baltic Sea Region and Western Russia

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The early evolutionary history of modern domestic horses (Equus caballus/Equus ferus caballus), known as the DOM2 lineage, is well documented due to numerous archaeological and ancient DNA (aDNA) studies. Although many uncertainties remain in the domestication timeline, current evidence suggests that the domestication of modern horses began in
Johanna Honka, Daniela Salazar, Arthur O. Askeyev, Igor V. Askeyev, Oleg V. Askeyev, Jouni Aspi, Gulshat Sh. Asylgaraeva, Markku Niskanen, Kristiina Mannermaa, Suvi Olli, Noora Piipponen, Giedrė Piličiauskienė, Dilyara N. Shaymuratova, Renat R. Valiev, Laura Kvist   +14 more
wiley   +1 more source

Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis

Frontiers in Immunology, 2019
Periapical periodontitis results from pulpal infection leading to pulpal necrosis and resorption of periapical bone. The current treatment is root canal therapy, which attempts to eliminate infection and necrotic tissue.
Yasir Dilshad Siddiqui, Kazuhiro Omori, Takashi Ito, Keisuke Yamashiro, Shin Nakamura, Kentaro Okamoto, Mitsuaki Ono, Tadashi Yamamoto, Thomas E. Van Dyke, Shogo Takashiba   +9 more
doaj   +1 more source

Dental pulp derived mesenchymal stromal cells

This book presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.? In this thoroughly updated and expanded second edition, the author covers mesenchymal stem cell
Yildirim, Sibel
core   +1 more source

Expression of high mobility group box 1 in inflamed dental pulp and its chemotactic effect on dental pulp cells

, 2014
High mobility group box 1 protein (HMGB1) is a chromatin protein which can be released extracellularly, eliciting a pro-inflammatory response and promoting tissue repair process.
Jiang, Hongwei, Zhang, Xufang, Huang, Yihua, Fan, Chen, Ling, Junqi, Gong, Qimei   +5 more
core   +1 more source