Results 101 to 110 of about 144,484 (342)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Tensile stress promotes the chondrogenic ability of condylar cartilage stem/progenitor cells in the temporomandibular joint via the Piezo1-Ca2+-Prkca pathway

Stem Cell Research & Therapy
Background Tensile force is a key regulator for condylar cartilage remodeling in the temporomandibular joint (TMJ), and this biomechanical characteristic underlies the mechanisms of mandibular growth modification in orthodontic practice.
Wuyi Gong, Zhihang Yue, Haojun Chu, Xiaohui Mi, Yongming Li   +4 more
doaj   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives

Advanced Materials, EarlyView.
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin, Liliang Ouyang, Khoon S. Lim, Antonella Motta, Devid Maniglio, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Accuracy of implant abutment level digital impressions using stereophotogrammetry in edentulous jaws: an in vitro pilot study

BMC Oral Health
Background In edentulous jaws, factors such as the number of implants, cross-arch distribution, and the angle among implants may affect the accuracy of the implant impression. This study explored factors influencing the accuracy of implant abutment-level
Yuan Zhou, Lang You, Zhen Fan
doaj   +1 more source

Effects of Dental Bleaching Agents on the Surface Roughness of Dental Restoration Materials. [PDF]

Medicina (Kaunas), 2023
Popescu AD, Tuculina MJ, Diaconu OA, Gheorghiță LM, Nicolicescu C, Cumpătă CN, Petcu C, Abdul-Razzak J, Rîcă AM, Voinea-Georgescu R.   +9 more
europepmc   +1 more source

Moving an incisor across the midline: A treatment alternative in an adolescent patient [PDF]

, 2011
A 13-year-old sought treatment for a severely compromised maxillary left central incisor and an impacted fully developed left canine. Extraction of both teeth became necessary.
Bosio, Jose A, Bradley, T. Gerard, Hefti, Arthur F   +2 more
core   +1 more source

Autonomous Implants

Advanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda, Marcel F. Kunrath, Ling Zhou Zhao, Mahdi Bodaghi, Armin Yousefi, Nureddin Ashammakhi   +5 more
wiley   +1 more source

Long-term application of silver nanoparticles in dental restoration materials: potential toxic injury to the CNS. [PDF]

J Mater Sci Mater Med, 2023
Wang K, Wang S, Yin J, Yang Q, Yu Y, Chen L.   +5 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source