Results 101 to 110 of about 51,358 (266)

p21 regulates the migration and polarization of macrophages in diabetic tooth extraction wound by regulating periodontal ligament fibroblasts

Kouqiang hemian waike zazhi
[Objective:] To explore the expression of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) in the healing process of tooth extraction wounds in diabetic mice and the effect on migration and polarization of macrophages.
ZHU Jiayu, YI Zimei, CHEN Siyi, DING Shuwen, YAN Jiayu, WU Junhua   +5 more
doaj   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Spatial and temporal distribution of p21 senescent cells in periodontal tissue of diabetic mice

Kouqiang hemian waike zazhi
[Objective:] To investigate the spatial and temporal distribution of p21 senescent cells in periodontal tissue and femur of diabetic mice. [Methods:] We constructed transgenic mice capable of tracing p21 senescent cells, used gel electrophoresis assay to
YI Zimei, REN Le, WEI Yu, CHEN Siyi, YAN Jiayu, WU Junhua   +5 more
doaj   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

Advanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang, Tingting Tong, Pengxi Shi, Xiaofan Chen, Chenhao Wang, Qingyuan Weng, Sihan Chen, Linli Que, Qi Chen, Yuehua Li, Qiang Zhu, Jiantao Li   +11 more
wiley   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Evaluating the Reasons of Amalgam Restoration Replacement in Esthetic and Restorative Department of Babol Dental School in 2013-14

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2015
Introduction: Dental amalgam is regarded as a popular restorative material. The purpose of this study is to investigate the reasons of replacing amalgam restorations in patients referring to Babol dental school within 2013-2014. Methods: In this analytic-
F Abolghasemzade, H Alaghehmand, H Khadem, R Judi   +3 more
doaj  

Effect of 3D-printing assisted micro-osteoperforations on the rate of canine retraction: a clinical investigation

BMC Oral Health
Objectives More time is often needed for adult orthodontic patients compared with juvenile counterparts due to lower tissue vitality. In some cases, the prolonged orthodontic treatment may cause a series of problems, such as enamel demineralization ...
Yangyifan Zhou, Qi Shao, Miaomiao Bie, Jingju Zhang, Han Shi, Feiwu Kang   +5 more
doaj   +1 more source

Multifunctional human serum albumin-crosslinked and self-assembling nanoparticles for therapy of periodontitis by anti-oxidation, anti-inflammation and osteogenesis

Materials Today Bio
Periodontitis is a chronic inflammatory disease that can result in the irreversible loss of tooth-supporting tissues and elevate the likelihood and intensity of systemic diseases.
Bangping Cao, Xuanbo Da, Wenjing Wu, Jian Xie, Xuejing Li, Xin Wang, Hui Xu, Jianfang Gao, Hui Yang, Jiansheng Su   +9 more
doaj   +1 more source

Dental Restoration [PDF]

, 2020
openaire   +1 more source