Results 101 to 110 of about 60,539 (341)

Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis

Journal of Nanobiotechnology
Temporomandibular joint osteoarthritis (TMJOA) is a multifaceted degenerative disease characterized by progressive cartilage degradation, chronic pain, and functional limitations of the TMJ, significantly affecting patients’ quality of life.
Xiaofeng Hu, Jian Xie, Jiansheng Su
doaj   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

Advanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong, Jae‐Kook Cha, Wasim Ahmed, Jaewan Kim, Minsup Kim, Kyung Tae Hong, Wonji Choi, Sunjoo Choi, Tae Hyeon Yoo, Hyun‑Ju An, Seung Chan An, Jaemin Lee, Jimin Choi, Sun‐Young Kim, Jun‐Seok Lee, Soonchul Lee, Junwon Choi, Jin Man Kim   +17 more
wiley   +1 more source

Effects of Dental Bleaching Agents on the Surface Roughness of Dental Restoration Materials. [PDF]

Medicina (Kaunas), 2023
Popescu AD, Tuculina MJ, Diaconu OA, Gheorghiță LM, Nicolicescu C, Cumpătă CN, Petcu C, Abdul-Razzak J, Rîcă AM, Voinea-Georgescu R.   +9 more
europepmc   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Dental restoration selection by students at southern Saudi Arabian universities. [PDF]

Bioinformation, 2022
Asiri W, Khan SD, Abdulkareem M, Abdullah H, Salah F, Nasseri K, Fayez F.   +6 more
europepmc   +1 more source

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

Advanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu, Xing‐Yue Zhou, Da‐Lian Qin, Qan Qiao, Qiao‐Zhi Wang, Shi‐Ying Li, Yun‐Fei Zhu, Ya‐Ping Li, Jiang‐Min Zhou, Hui Cai, Fei‐Hong Huang, Lu Yu, Long Wang, An‐Guo Wu, Jian‐Ming Wu, Xiao‐Gang Zhou   +15 more
wiley   +1 more source

A comprehensive biomechanical evaluation of length and diameter of dental implants using finite element analyses: A systematic review

Heliyon
Background: With a wide range of dental implants currently used in clinical scenarios, evidence is limited on selecting the type of dental implant best suited to endure the biting force of missing teeth.
Piaopiao Qiu, Rongkai Cao, Zhaoyang Li, Zhen Fan   +3 more
doaj  

AESTHETIC CONCEPTS IN CONTEMPORARY DENTAL MEDICINE

Romanian Journal of Oral Rehabilitation, 2014
In our days, the aim of the dental medicine is not only to realize functional restoration, but also aesthetic prosthesis. Modern materials and emerging peak technologies allow today's dental restorations achievement that meets the highest aesthetic ...
Diana Antonela Diaconu, Anca Mihaela Viţalariu, Monica Silvia Tatarciuc   +2 more
doaj  

Regular Dental Check-Ups Are Associated with Choosing Uninsured Dental Restoration/Prosthesis Treatment in Japan. [PDF]

Healthcare (Basel), 2023
Oshima K.
europepmc   +1 more source

Scanning acoustic microscopy study of titanium-ceramic interface of dental restorations [PDF]

, 1998
Russell R. Wang, Eric M. Meyers, J. Lawrence Katz   +2 more
openalex   +1 more source