Results 111 to 120 of about 261,861 (304)

Public health and dental caries in young children in deprived communities in Scotland [PDF]

open access: yes, 2012
Dental  caries  is  the  most  prevalent  disease  worldwide,  and  is  caused  by  a  complex  interaction of tooth susceptibility, nutrition and the oral environment.  In young children it  can have a major impact on their quality of life, and is the 
Chambers, Stephanie
core  

Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis

open access: yesAdvanced Science, EarlyView.
Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan   +21 more
wiley   +1 more source

Role of School-Based Health Centers Under Universal Coverage for Children and Youth in California: Issues and Options [PDF]

open access: yes, 2007
Examines challenges of and provides suggestions for a universal model of health care delivery for all children and youth in California.
Nancy Torrey, Steve Rosenberg
core  

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

Effectiveness of School Dental Health Programs: A Review with Insights from India

open access: yesNational Board of Examinations Journal of Medical Sciences
Schools provide a vital platform for dental health promotion since children spend a large amount of time there, which shapes their habits and overall health.
Diksha Sharma   +5 more
doaj   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as
Zengqing Liu   +23 more
wiley   +1 more source

You and Your Neighbor [PDF]

open access: yes, 1949
PDF pages ...
Archibald, Roy   +7 more
core  

Transitioning from dental school [PDF]

open access: yesBritish Dental Journal, 2020
Bahia, G., Janjua, U., Ashfaq, N.
openaire   +2 more sources

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

open access: yesAdvanced Science, EarlyView.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao   +11 more
wiley   +1 more source

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