Results 21 to 30 of about 1,572 (139)
Peri‐implantitis—Is it mainly a clinician‐initiated complication of implant therapy?
Abstract Aim The high prevalence of peri‐implantitis is concerning, with a growing consensus that the majority of cases are complications initiated by clinician‐related errors rather than classic pathology. A primary predisposing factor for peri‐implantitis is exposure of the micro‐rough implant surfaces to the peri‐implant sulcus after treatment ...
Stephen T. Chen +9 more
wiley +1 more source
Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning +6 more
wiley +1 more source
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim +9 more
wiley +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
ABSTRACT Microplastics have been identified in hundreds of species, with evidence of trophic transfer via contaminated prey. Sarasota Bay common bottlenose dolphins (Tursiops truncatus) serve as sentinels of coastal pollution, including plastics and chemical plasticizers. Previous research confirmed microplastic ingestion in these dolphins (100.0%, n =
Estella Martin +12 more
wiley +1 more source
Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease
Abstract INTRODUCTION Sleep disruption is an early feature of Alzheimer's disease (AD), but the cellular mechanisms linking amyloid pathology to sleep loss remain unclear. METHODS Electroencephalography/electromyography (EEG/EMG) recordings, quantitative EEG analysis, and sleep deprivation were performed in APPswe/PSEN1dE9 (APP/PS1) mice at different ...
Nicholas J. Constantino +9 more
wiley +1 more source
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing +4 more
wiley +1 more source
ABSTRACT Sleep is essential for normal physiological functioning, and sleep deprivation is typically compensated by increasing subsequent sleep duration and/or intensity. However, a recent study showed that barnacle geese (Branta leucopsis) exhibit seasonal variation in sleep homeostasis, with full recovery of sleep after sleep deprivation in summer ...
Robin Pijnacker +4 more
wiley +1 more source
Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim +8 more
wiley +1 more source
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki +4 more
wiley +1 more source

