Results 131 to 140 of about 64,936 (312)

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Influence of clinical and socioeconomic indicators on dental trauma in preschool children [PDF]

open access: diamond, 2014
Patrícia Corrêa‐Faria   +3 more
openalex   +1 more source

Mechano‐Bactericidal Surfaces Achieved by Epitaxial Growth of Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
Mechano‐bactericidal surfaces based on metal–organic frameworks (MOFs) are designed using a MOF‐on‐MOF strategy. Two methods of MOF surface assembly, in situ growth and ex situ dropcasting, are applied. Distinct mechano‐bactericidal actions are discussed, including stretching, impaling, and mechanical injury. Abstract Mechano‐bactericidal (MB) surfaces
Zhejian Cao   +7 more
wiley   +1 more source

Avaliação do conhecimento da abordagem de trauma dental pelos profissionais de creches

open access: diamond, 2009
Maurício Bacarin Silva   +5 more
openalex   +2 more sources

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

open access: yesAdvanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu   +13 more
wiley   +1 more source

Knowledge and Attitude of Dental Trauma Among Dental Students in Thrace Region of Turkiye [PDF]

open access: yesJournal of Oral Health and Oral Epidemiology
Background and aimThe study aimed to determine the level of knowledge of Trakya University Faculty of Dentistry 4th and 5th grade students about the diagnosis and clinical management of dental traumatic injuries and to evaluate the effects of factors ...
İrem Çetinkaya, Neslihan Ozveren
doaj  

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

open access: yesAdvanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan   +10 more
wiley   +1 more source

The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair

open access: yesAdvanced Science, EarlyView.
Synthesis of an innovative three‐layer composite antiadhesion barrier (plasmid DNA@E–H–E′) is schematically illustrated, highlighting its reactive‐oxygen‐species‐responsive, unidirectional interleukin‐37 delivery to enhance fibroblast autophagy, thereby effectively preventing tendon adhesion and promoting scarless tendon repair.
Zhenyu Sun   +5 more
wiley   +1 more source

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