Results 51 to 60 of about 29,749 (310)

Assessment of the antibacterial effect of eighth-generation dentin bonding agent supplemented with propolis on Streptococcus mutans: An in vitro study

Scientific Dental Journal, 2023
Background: The major challenge associated with composite resin is microleakage, which leads to gaps and secondary caries. The prevalent organism responsible for secondary caries is Streptococcus mutans.
Deepa Singh, Moksha Nayak, Vishnuja V R Nair   +2 more
doaj   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

Advanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang, Yijin Hou, Likun Cui, Huiqi Yu, Rong Liu, Junhao Sui, Zhong Zheng, Lu Liu, Jie Chen, Mengchen Chen, Chen Ding, Shuogui Xu, Sheng Xu, Hao Zhang   +13 more
wiley   +1 more source

The Post–endodontic Adhesive Interface: Theoretical Perspectives and Potential Flaws [PDF]

, 2018
Introduction The aim of this review was to analyze the potential of successful bonds of endodontic posts to radicular dentin as well as the limitations of the post–endodontic adhesive interface. Methods The MEDLINE/PubMed and Web of Science electronic
He, Jianing, Maroulakos, Georgios, Nagy, William W.   +2 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Dentinogenesis Imperfekta : Aspek Genetika Molekular, Klasifikasi dan Upaya Penanggulangannya

Journal of Dentistry Indonesia, 2015
Dentinogenesis Imperfecta (DI) is a hereditary simple autosomal dominant disorder showing abnormalities in the dentin of developing teeth and occuring at a rate of about 1 in 8000 births affecting both primary and secondary dentitions.
Elza Ibrahim Auerkari, A. Surjadi, S. Mangoendjaja   +2 more
doaj   +1 more source

Efficacy of a Dissolvable Strip with Calcium Sodium Phosphosilicate (NovaMin®) in Providing Rapid Dentine Hypersensitivity Relief [PDF]

, 2019
Objective To evaluate the efficacy of a dissolvable strip containing 15% w/w calcium sodium phosphosilicate (CSPS) (Novamin®) in providing rapid relief from dentine hypersensitivity (DH).
Amini, Pejmon, Atassi, Mounir, Gallob, John, Ling, Martin R., Patil, Avinash   +4 more
core   +2 more sources

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

A Study of the Effects of Medical Dental Laser and Diamond Drill on Dentin Tissue during Dental Restoration Based on Spectral Imaging and Multivariate Analysis of Synchrotron FTIR Microspectroscopy Data

Photonics, 2023
In our work, the effect of a dental Er:YAG pulsed laser and a diamond cylindrical drill with a turbine handpiece on dentin tissue was studied using spectral imaging.
Pavel Seredin, Dmitry Goloshchapov, Nikita Buylov, Dmitry Nesterov, Vladimir Kashkarov, Yuri Ippolitov, Ivan Ippolitov, Sergey Kuyumchyan, Jitraporn Vongsvivut   +8 more
doaj   +1 more source