Sex- and Age-related Differences in Primary and Secondary Dentin Formation [PDF]
Clinical studies carried out on dentin thickness in adults, as well as experimental studies carried out on ovariectomized animals, indicate that odontoblast activity, like that of osteoblastic cells, differs in the two sexes. To examine the evidence for differences in odontoblast activity before puberty, we have measured dentin thickness and other ...
U, Zilberman, P, Smith
openaire +2 more sources
Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
We have evaluated and compare the effect of different exogenous MMP inhibitors on adhesive physical properties of dental adhesives, bond strength, micro permeability and MMP substrate activity. 180-grit Sic paper was used to obtain the superficial dentin
Pei Zheng, Hui Chen
doaj +1 more source
The Histochemical Distribution of MMP-2 in the Coronal Dentin of Exfoliated Human Upper Deciduous Teeth [PDF]
Introduction: Matrix Metalloproteinase-2 (MMP-2) is an enzyme synthesized by odontoblast and acts as a proteolytic enzyme capable of digesting extracellular matrix protein gelatin/collagen of dentin and is involved in the pathogenesis of dental caries ...
Riyam Ashour, Haider Mubarak
doaj +1 more source
Phosphorylation regulates the secondary structure and function of dentin phosphoprotein peptides [PDF]
Dentin phosphoprotein (DPP) is the most acidic protein in vertebrates and structurally is classified as an intrinsically disordered protein. Functionally, DPP is related to dentin and bone formation, however the specifics of such association remain unknown. Here, we used atomistic molecular dynamics simulations to screen selected binding domains of DPP
Eduardo, Villarreal-Ramirez +5 more
openaire +2 more sources
Ultrastructure of Dentin Matrix in Heritable Dentin Defects [PDF]
Heritable dentin defects form a group of diseases which exclusively affect dentin among the various dental tissues. While one type is associated with the generalized connective tissue disorder, osteogenesis imperfecta, other types occur as single traits.
Waltimo, J., Lukinmaa, P. -L., Ranta, H.
core +1 more source
Adhesive systems and secondary caries formation: Assessment of dentin bond strength, caries lesions depth and fluoride release [PDF]
Objectives. The present study evaluated the microtensile bond strength and caries formation on adhesive/dentin interfaces before and after dynamic chemical formation of secondary caries. Methods.
Bedran-Russo, AKB +4 more
core +1 more source
Abundance of MMPs and cysteine cathepsins in caries-affected dentin [PDF]
Degradation of dentin matrix components within caries dentin has been correlated with the activity of host-derived proteases, such as matrix metalloproteases (MMPs) and cysteine cathepsins (CTs). Since this relationship has not been fully established, we
Tersariol, I. L. +7 more
core +1 more source
ToF-SIMS Analysis of Demineralized Dentin Biomodified with Calcium Phosphate and Collagen Crosslinking: Effect on Marginal Adaptation of Class V Adhesive Restorations [PDF]
This study aimed to assess the effect of biomodification before adhesive procedures on the tooth-restoration interface of class V restorations located in caries-simulated vs. sound dentin, and the quality of dentin surface by time-of-flight secondary ion
Ivo Krejci +3 more
core +1 more source

