Results 51 to 60 of about 101,964 (352)

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

JBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan   +7 more
wiley   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

SCANNING ELECTRON MICROSCOPIC INVESTIGATION OF DENTINAL TUBULES IN Cebus apella DENTIN

Ciência Animal Brasileira, 2009
The aim of the study was to investigate the number and diameter of the Cebus apella dentinal tubules. The roots of the Cebus apella teeth were examined in specific tooth locations: the apical, middle and cervical dentin.
Rafael Rodrigues Lima, Leila Marques Araújo, Priscilla Rocha Affonso, Kalena Melo Maranhão, João Humberto Antoniazzi, Suely Santos Lamarão   +5 more
doaj   +1 more source

Role of Dentin MMPs in Caries Progression and Bond Stability

Journal of dentistry research, 2015
Dentin can be described as a biological composite with collagen matrix embedded with nanosized hydroxyapatite mineral crystallites. Matrix metalloproteinases (MMPs) and cysteine cathepsins are families of endopeptidases.
A. Mazzoni, L. Tjäderhane, Vittorio Checchi, R. Lenarda, Tuula Salo, F. R. Tay, D. Pashley, L. Breschi   +7 more
semanticscholar   +1 more source

Molecular mechanisms, physiological roles, and therapeutic implications of ion fluxes in bone cells: Emphasis on the cation‐Cl− cotransporters

Journal of Cellular Physiology, Volume 237, Issue 12, Page 4356-4368, December 2022., 2022
Ion transport systems in the membranes of osteoblasts and osteoclasts play a key role in bone remodeling by coordinating the movement of Ca2+, PO42−, and H+ ions in and out of the osseous matrix. Based on the evidence available, the cation‐Cl− cotransporters could act as unexpectedly important players in this regard.
Alexandre P. Garneau, Samira Slimani, Ludwig Haydock, Thy‐René Nsimba‐Batomene, Florence C.M. Préfontaine, Mathilde M. Lavoie, Laurence E. Tremblay, Marie‐Jeanne Fiola, Fabrice Mac‐Way, Paul Isenring   +9 more
wiley   +1 more source

Biomimetic remineralization of dentin

口腔疾病防治, 2020
In recent years, due to precise control of the amorphous mineral precursor in the demineralization of dentine collagen fibers in orderly deposition, forming apatite crystals similar to the natural mineralized dentin, the bottom-up remineralization ...
SONG Qun, LIU Xiaochen, MA Yuxuan, WANG Chenyu, JIAO Kai, NIU Lina   +5 more
doaj   +1 more source

The benefits of structural disorder in natural cellular solids [PDF]

arXiv, 2021
Structural cellular materials in nature, such as wood, trabecular bone, corals, and dentin combine complex biological functions with structural roles, such as skeletal support and impact protection1,2. They feature complex structural hierarchies from nano- to macroscale that enable optimization of both strength and toughness (flaw tolerance ...
arxiv  

Effects of silver diammine fluoride on bond strength of adhesives to sound dentin.

Dental materials journal, 2018
This study evaluated bonding of adhesives to dentin treated with silver diammine fluoride (SDF). Micro-shear bond strength (MSBS) to sound human dentin was investigated for 3 adhesive systems: Clearfil SE bond 2 (CSE), and Scotchbond Universal in self ...
P. Lutgen, D. Chan, A. Sadr
semanticscholar   +1 more source

Electromechanical Imaging of Biological Systems with Sub-10 nm Resolution [PDF]

, 2005
Electromechanical imaging of tooth dentin and enamel has been performed with sub-10 nm resolution using piezoresponse force microscopy. Characteristic piezoelectric domain size and local protein fiber ordering in dentin have been determined. The shape of a single collagen fibril in enamel is visualized in real space and local hysteresis loops are ...
arxiv   +1 more source

Dentin hassasiyet giderici ajanların tek aşamalı bir self-etch adezivin makaslama bağlanma dayanımına etkisi

Cumhuriyet Dental Journal, 2014
Amaç: Bu çalışmanın amacı içerikleri farklı 12 adet dentin hassasiyet giderici ajanın (DHGA) bir self-etch adeziv rezinin makaslama bağlanma dayanımına etkisinin belirlenmesidir.
Cemal Yeşilyurt, Gunes Bulut Eyüboğlu
doaj   +1 more source