Results 91 to 100 of about 7,940 (235)

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton

open access: yesInternational Endodontic Journal, Volume 58, Issue 6, Page 873-889, June 2025.
Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.
Xiaolin Li   +7 more
wiley   +1 more source

Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and Apoptosis

open access: yesCell Proliferation, Volume 58, Issue 5, May 2025.
OPTN interacts with NRF2 to facilitate the AKT/DRP1‐mediated regulation of mitochondrial fission in the cytoplasm of SCAPs, promoting tooth root mineralisation. Additionally, OPTN maintains NRF2's nuclear translocation, enhancing the transcriptional regulation of downstream BCL2, ultimately leading to the inhibition apoptosis in SCAPs and regulate ...
Haojie Liu   +9 more
wiley   +1 more source

Structural Variants in COL1A1 and COL1A2 in Osteogenesis Imperfecta

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 3, March 2025.
ABSTRACT Osteogenesis Imperfecta (OI) is a heterogeneous skeletal dysplasia characterized by bone fragility, skeletal deformities, and short stature. Most commonly, it is caused by autosomal dominant variants in the type I collagen genes, COL1A1 or COL1A2.
Dominyka Batkovskyte   +10 more
wiley   +1 more source

Biomimetic Polymer Film with Brilliant Brightness Using a One‐Step Water Vapor–Induced Phase Separation Method [PDF]

open access: yes, 2019
The scales of the white Cyphochilus beetles are endowed with unusual whiteness arising from the exceptional scattering efficiency of their disordered ultrastructure optimized through millions of years of evolution.
Guo, Jing   +7 more
core   +2 more sources

Promoting dentinogenesis of DPSCs through inhibiting microRNA-218 by using magnetic nanocarrier delivery

open access: yesJournal of the Formosan Medical Association, 2019
Purpose: The purposes of this study are to explore the roles of microRNA-218 (miR-218) delivered by a newly designed magnetic nanocarrier: GCC-Fe3O4 (GCC-Fe) in dentinogenesis potentials of human dental pulp stem cells (DPSCs).
Karen Chang   +3 more
doaj  

Potassium Currents Activated by Depolarization in Odontoblasts

open access: yesFrontiers in Physiology, 2017
Increased intracellular free Ca2+ concentrations elicit plasma membrane depolarization, which leads to the activation of K+ currents. However, the precise properties of K+ currents activated by depolarization in odontoblasts remain to be elucidated.
Yuki Kojima   +6 more
doaj   +1 more source

Dental management of a child with a rare bone disorder: a case report with a six-year follow up

open access: yesRGO: Revista Gaúcha de Odontologia, 2020
Osteogenesis imperfecta is a rare genetic disorder involving abnormal type I collagen composition that compromises bone and collagen-rich tissues. Individuals with Osteogenesis imperfecta exhibit oral and systemic abnormalities, including dentinogenesis ...
Suélen Alves TEIXEIRA   +5 more
doaj   +1 more source

The effect of fluoride on enamel and dentin formation in the uremic rat incisor [PDF]

open access: yes, 2008
Renal impairment in children is associated with tooth defects that include enamel pitting and hypoplasia. However, the specific effects of uremia on tooth formation are not known.
A Al Nowaiser   +28 more
core   +1 more source

Differential Expression of Hard Tissue Proteins in Hypomineralized Second Primary Molars in Comparison to Normal Teeth

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 1, February 2025.
ABSTRACT Objective This study aims to identify the proteins in hypomineralized second primary molars (HSPMs) and correlate their function in Amelogenesis. HSPM is a qualitative defect of the enamel of the second primary molars with no clear etiology.
Sharon Jessica   +9 more
wiley   +1 more source

Haploinsufficiency of Dspp Gene Causes Dentin Dysplasia Type II in Mice

open access: yesFrontiers in Physiology, 2020
Dentin dysplasia (DD) and dentinogenesis imperfecta (DGI) patients have abnormal structure, morphology, and function of dentin. DD-II, DGI-II, and DGI-III are caused by heterozygous mutations in the dentin sialophosphoprotein (DSPP) gene in humans ...
Ce Shi   +17 more
doaj   +1 more source

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