Results 11 to 20 of about 4,054 (202)

Personalized Bonding Approach for Full‐Mouth Adhesive Rehabilitation in Dentinogenesis Imperfecta [PDF]

Clin Case Rep
Dentinogenesis imperfecta is a rare genetic disorder impacting dentin structure, with an incidence of 1 in 6000 to 1 in 8000 individuals. This condition alters the tooth's color and structure, affecting patients aesthetically, functionally, and socially.
Clark C, Kérourédan O, Massé L.
europepmc   +4 more sources

A Novel Variant in Dentin Sialophosphoprotein (DSPP) Gene Causes Dentinogenesis Imperfecta Type III: Case Report. [PDF]

Mol Genet Genomic Med
Background Hereditary dentin defects are a group of autosomal dominant disorders characterized by developmental abnormalities in dentin formation and mineralization. They can be categorized into dentin dysplasia and dentinogenesis imperfecta.
Wang Y, Xu X, Ding Y, Yuan G.
europepmc   +4 more sources

Prevalence of Dentinogenesis Imperfecta in a French Population. [PDF]

J Int Soc Prev Community Dent, 2017
Dentinogenesis imperfecta is a genetic disorder of the dentin occurring during the tooth development. It leads to many structural changes that can be identified clinically (brownish colored teeth, cracked enamel) and radiologically (globular crown, cervical constriction, short roots, and obliterated pulp chamber and/or root canals).
Cassia A, Aoun G, El-Outa A, Pasquet G, Cavézian R.   +4 more
europepmc   +6 more sources

Dentinogenesis imperfecta type II- genotype and phenotype analyses in three Danish families. [PDF]

Mol Genet Genomic Med, 2018
BackgroundDentinogenesis imperfecta (DI) is a rare debilitating hereditary disorder affecting dentin formation and causing loss of the overlying enamel. Clinically, DI sufferers have a discolored and weakened dentition with an increased risk of fracture.
Taleb K, Lauridsen E, Daugaard-Jensen J, Nieminen P, Kreiborg S.   +4 more
europepmc   +5 more sources

Blue Sclera to Brittle Bones: A Rare Case of Osteogenesis Imperfecta With Dentinogenesis Imperfecta and Nephrocalcinosis. [PDF]

J Investig Med High Impact Case Rep
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility. Its association with dentinogenesis imperfecta (DI) is well documented, but the concurrent presentation with nephrocalcinosis is uncommon and poorly understood.
Hayat S, Mayan AR, Khan MW, Hayat QJ.
europepmc   +3 more sources

Unravelling the Genetic Basis of Dentinogenesis Imperfecta

International Dental Journal, 2023
Aim or Purpose: Dentinogenesis imperfecta (DI) is an autosomal dominant genetic disorder affecting dentine formation. This study aimed to perform mutational analysis in individuals with DI to unravel its molecular mechanisms. Materials and Methods: The University of Western Australia Human Research Ethics Committee (RA/4/20/4203) approved this genetic ...
Dr Maleeha Gilani, Associate Professor Robert Anthonappa   +1 more
doaj   +4 more sources

Mutant Dentin Sialophosphoprotein Causes Dentinogenesis Imperfecta. [PDF]

J Dent Res, 2019
Dentin sialophosphoprotein (DSPP) is an extracellular matrix protein highly expressed by odontoblasts in teeth. DSPP mutations in humans may cause dentinogenesis imperfecta (DGI), an autosomal dominant dentin disorder. We recently generated a mouse model (named “ DsppP19L/+ mice”) that expressed a mutant DSPP in which the proline residue at position ...
Liang T, Zhang H, Xu Q, Wang S, Qin C, Lu Y.   +5 more
europepmc   +5 more sources

Dentinogenesis imperfecta type II dentin: nanostructural mechanics analysis [PDF]

BMC Oral Health
Objectives This study investigated the nanomechanical properties, microstructure, and composition of dentinogenesis imperfecta type II (DGI-II) peritubular dentin (PTD) and intertubular dentin (ITD) and examined the correlations between them.
Jia G, Tianle J, Haofu J, Wenxia C, Junhao T, Mengjia Y, Yixin M, Yang C, Xia W, Shuomin C, Shengbin H.   +10 more
europepmc   +3 more sources

Minimally invasive orthodontics: elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta. [PDF]

Ann Stomatol (Roma), 2017
AIM: The aim of the study was to report the use of an elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta, second class malocclusion, deep bite and lower arch crowding from the deciduous dentition to permanent one. CASE
Ierardo G, Luzzi V, Nardacci G, Vozza I, Polimeni A.   +4 more
europepmc   +3 more sources

Morphological and Ultrastructural Collagen Defects: Impact and Implications in Dentinogenesis Imperfecta. [PDF]

Dent J (Basel), 2023
Collagen is the building block for the extracellular matrix in bone, teeth and other fibrous tissues. Osteogenesis imperfecta (OI), or brittle bone disease, is a heritable disorder that results from defective collagen synthesis or metabolism, resulting ...
Gadi LSA, Chau DYS, Parekh S.
europepmc   +3 more sources